Results 91 to 100 of about 13,180,176 (302)
Sports Medicine - OpenBackground Globally, just one in five adolescents meet physical activity guidelines and three-quarters of the school day is spent sitting. It is unclear which types of school-based interventions strategies increase physical activity and reduce sedentary ...
Ana María Contardo Ayala +9 more
doaj +1 more source
Effects of beetroot juice supplementation on intermittent high-intensity exercise efforts
Journal of the International Society of Sports Nutrition, 2018 Beetroot juice contains high levels of inorganic nitrate (NO3 −) and its intake has proved effective at increasing blood nitric oxide (NO) concentrations.
Raúl Domínguez +8 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
, 2015 Objective: The health benefits of physical activity participation and minimising sedentary behaviours are well known. As well, evidence exists for the relationship between physical activity and health-related quality of life.
Duncan, Mitch J. +7 more
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The clustering of readiness to adopt healthy nutrition and physical activity behaviours
, 2011 Purpose: To determine if the stage-of-change categorisation for four healthy behaviours: decreasing sugary drink intake, increasing physical activity level, reducing dietary fat consumption and increasing fruit and vegetable intake, is similar for ...
Cook, Amelia (R17687) +3 more
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
The impact of retirement on physical activity [PDF]
, 2005 Most adults do not achieve the levels of physical activity currently recommended for a healthy lifestyle. Population surveys suggest that there is a linear decline of activity levels with age, yet physical activity has many health benefits for older ...
Der, G. +3 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source