Results 81 to 90 of about 515,070 (285)

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Physical and Mechanical Properties of the Muds of the Fergoug Dam

open access: yesEngineering, Technology & Applied Science Research, 2014
Volumes of dredged sediments are rather considerable and are estimated approximately 600 million m3 per year worldwide. These can represent a very interesting source of raw materials, in particular for a sector consuming aggregates such as civil engineering.
Benaissa, A.   +4 more
openaire   +3 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Influence of Furfurylation on Practical Properties of Beech Plywood [PDF]

open access: yesIranian Journal of Wood and Paper Industries, 2016
In this study, the influence of Furfurylation on practical properties of beech plywood investigated. Furfurylation of beech layers were performed by impregnation and heat catalyze up to 30% and 70% weight percent gain. Plywood specimens made by 2 resins (
Aisona Talaei, mohammad Tavakoliyan
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Mechanical and metallurgical properties of two-layered diamalloy 4010 and 2002 HVOF coating [PDF]

open access: yes, 2011
Diamalloy 4010, which is iron/molybdenum blend, is resistive to wear and Diamalloy 2002 is resistive to corrosion and wear. However, combination of these powders in layered structure, may offer advantages over the individual powders.
AL-Shehri, Yasser Abdullah
core   +1 more source

Physical and mechanical properties of membrane Polyacrylonitrile

open access: yesMATEC Web of Conferences, 2017
Tensile test is a method used to measure the strength of a material by providing the burden of the opposing forces in a straight line. This experiment used to measure a material’s mechanical strength against a static force which is given slowly.
Mataram Agung   +3 more
doaj   +1 more source

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