Results 61 to 70 of about 548,338 (294)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Physical And Mechanical Properties Of Sea Ice In Bending [PDF]
KnE Materials Science, 2016 <p>The work presents the study of changes in the physical and mechanical properties of sea ice in bending. Strength limit σ<sub>в</sub> and deformation module Е<sub>в</sub> of ice under bending are conditional mechanical characteristics of sea ice.
Koshkin, S. V., Taranukha, N. A.
openaire +2 more sources
Variation on thermal damage rate of granite specimen with thermal cycle treatment
High Temperature Materials and Processes, 2019 Temperature significantly affects the physical and mechanical properties of granite. To have a comprehensive understanding of the thermal cycle effect on uniaxial compressive strength (UCS) and thermal damage rate, a series of thermal cycle experiments ...
Xu Chenchen +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Ultrasonic evaluation of the physical and mechanical properties of granites [PDF]
Ultrasonics, 2008 Masonry is the oldest building material that survived until today, being used all over the world and being present in the most impressive historical structures as an evidence of spirit of enterprise of ancient cultures. Conservation, rehabilitation and strengthening of the built heritage and protection of human lives are clear demands of modern ...
Vasconcelos, Graça +3 more
openaire +3 more sources
Mechanical and physical properties of HDF workpieces.
, 2018 Mechanical and physical properties of HDF workpieces.
Pingxiang Cao (5746559) +5 more
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The effect of zinc oxide filler on mechano-physical and electromechanical properties of PVDF [PDF]
, 2020 This study deals with the effect of star-like zinc oxide (ZnO) filler addition into poly(vinylidene fluoride) (PVDF) matrix on its structural and physical properties with the consequences to mechanical energy harvesting performance.
Bažant, Pavel +3 more
core +2 more sources
Wound healing of tendon--I. Physical, mechanical and metabolic changes [PDF]
, 1980 The wound healing process of New Zealand rabbit extensor digitorum communis tendon was studied from the fifth through thirteenth post-surgical day by concurrent observation of physical, mechanical, and biochemical properties.
Block, Walter D. +5 more
core +1 more source