Results 31 to 40 of about 165,136 (217)

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effect of ionic liquids on tribological properties of water-iubricated nitrile rubber rubber

Hecheng xiangjiao gongye, 2021
Nitrile rubber(NBR)-based composites modified with three kinds of imidazolium-based ionic liquids were prepared by mechanical mixing method. Curing characteristics, dynamic mechanical properties, physical and mechanical properties and friction ...
WANG Shan, PEI Gao-lin, SU Zheng-tao
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Effect of additon amount of carbon black on curing characteristics, physical and mechanical properties, and dynamic mechanical properties of tetrafluoroethylene-propylene rubber

Hecheng xiangjiao gongye
The effect of carbon black addition amount on curing characteristics of tetrafluoroethylene-propylene rubber compounds and physical and mechanical properties, dynamic mechanical properties and high- and low-temperature properties of the vulcanizates were
GONG Zi-qing, LI Bo, HE Lian-cheng, HUANG Xi-dai, ZHAO Hong-guo, WU Yu, HU Hai-hua, ZHOU Lei
doaj   +1 more source

Effects of different vulcanization systems on physical and mechanical properties and electrical insulation of ethylene propylene diene monomer

Hecheng xiangjiao gongye, 2022
Ethylene propylene diene monomer (EPDM) vulcanizates were prepared by sulfur vulcanization, semi-effective vulcanization, sulfur carrier vulcanization, organic peroxide vulcanization and composite vulcanization systems respectively.
JIANG Guang-zhao; LIU Da-chen; XU Lin-chao
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

THE RELATIONSHIP OF THE ELASTIC AND STRENGTH PROPERTIES OF CLAYDITE-CONCRETE AND ITS COMPONENTS

Nauka ta progres transportu, 2008
The paper is dealt with mutual influence of resilient and cohesion characteristics of the mortar ingredients of lightweight aggregate concrete on its physical and mechanical properties.
M. O. Nikiforova, O. F. Maslyaev
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source