Results 61 to 70 of about 1,360,407 (261)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Motriz: Revista de Educacao FisicaHealth problems related to a low level of physical activity (PA) in children and adolescents have prompted research into extracurricular PA programs. This study was designed to determine the effects of two different levels of PA on the health-related ...
Sergio Reloba Martínez +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Journal of Education, Health and Sport, 2017 The article presents the results of determining the indicators of physical condition and physical fitness of schoolchildren, aged 15-16, necessary to elaborate a health and recreational activities program.
Таrаs Blistiv
doaj
Influential Factors of Taekwondo Achievement in Regional Sport Competition
Physical Activity JournalEndurance is one of the most influential factors in achieving high-performance athletes. The level of maximum oxygen volume or VO2Max describes endurance. VO2Max is the ability to consume oxygen during physical activity.
Ahad Agafian Dhuha +4 more
doaj +1 more source
Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2016 Physical functioning of average and high intensity is an important component of mature men’s health and longevity. For highly intensive physical functioning organism’s physical fitness is required.
O.B. Pryshva
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Analysis of physical condition components of petanque athletes
Sriwijaya Journal of SportResearch Problems: Physical condition is a fundamental component supporting performance in precision sports such as petanque. Optimal endurance, balance, strength, and flexibility are required to maintain stability, accuracy, and consistency during ...
Arsan Firdaus Ariyanto +3 more
doaj +1 more source