Results 91 to 100 of about 38,082 (273)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Papel dos receptores da adenosina em um modelo animal do transtorno de déficit de atenção e hiperatividade [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2010O transtorno de déficit de atenção e hiperatividade (TDAH) é uma das doenças psiquiátricas mais ...
Pandolfo, Pablo
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Metabolic and physiological changes during and after vaquejada exercise in horses
Medicina Veterinária, 2019 Physiological and metabolic evaluations of equine sports have been conducted to define parameters or biomarkers for performance evaluation, clinical diagnosis and predict fatigue and overtraining.
Monica Miranda Hunka +5 more
doaj
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
, 1980 A continuous vertical ladder ergometer for small animals has been developed. This device, operating at a (variable) downward velocity, obliges the subject animal to climb continuously, thus imposing a steady quantifiable work rate or power output.
J. C. Russell +2 more
core +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
The Welfare of Cattle kept for Beef Production
, 2001 Content: 1) Introduction 2) State of the Industry 3) Hosing Systems 4) Behaviour of Cattle 5)Effect of Housing on the Welfare of the Animals 6) the effects of Management on Cattle Welfare 7)Futere Research Needed 8) Conclusions 9 ...
Scientific Committee on Animal Health and Animal Welfare
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Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Animal Enclosure Air-Conditioning System Using Radiant Cooling
, 2007 Destruction of the ozone layer of the atmosphere and the problem of global warming due to refrigerants used by vapour compression HVAC systems accompanied by the general need to reduce the primary energy consumption, suggests giving attention to ...
Abdalla, Salah Ahmed
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