The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Prejuízo no processamento olfatório emocional em um modelo animal de doença de Parkinson e o ambiente de criação como estratégia protetora [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2011Os sintomas pré-motores da doença de Parkinson (DP) englobam diversas alterações emocionais ...
França, Sanmara de Lima
core
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
The Effect of a Strength Training Session on Alpha Phytoprotein, Gamma Glutamyl Transferase and Alkaline Phosphatase in People with Regular Training and Forced Non-Training Due to Covid-19 [PDF]
Mohammadyari S, Hadi H, Saberi Y. Investigation of physiological effects (immune system) of Exercise in COVID-19 epidemic; By providing a training protocol (Systematic review). Journal of Applied Health Studies in Sport Physiology 2021; 8(1): 88-101.
mohammad amini +3 more
doaj
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Papel dos corticosteroides no processamento de memórias aversivas: consequências bidirecionais no condicionamento olfatório de medo [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaO funcionamento anormal dos receptores corticosteroides no cérebro tem sido apontado como peça fundamental para o ...
Souza, Rimenez Rodrigues de
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Animal Flow as a Supplementary Training Tool for Basketball: A 12-Week Randomized Controlled Trial
This study aimed to evaluate the effects of integrating Animal Flow into traditional basketball training on physical performance in university athletes, focusing on agility, core endurance, proprioceptive awareness, repeated sprint ability, flexibility ...
Buğra Çağatay Savaş +9 more
doaj +1 more source
An Operant Conditioning Task to Assess the Choice between Wheel Running and Palatable Food in Mice
Wheel running, especially in the homecage, has been widely used to study the neurobiology of exercise because animal tends to use it voluntarily.
Bastien Redon +3 more
doaj +1 more source
«Sun does not always shine and the wind does not always blow» (Rifkin, 2011). Looks like we have a problem. Our problem is time. It is an ancient human problem to want to predict.
Teodoro Georgiadis
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

