Application of the Physical Disector Principle for Quantification of Dopaminergic Neuronal Loss in a Rat 6-Hydroxydopamine Nigral Lesion Model of Parkinson's Disease [PDF]
Frontiers in Neuroanatomy, 2017 Stereological analysis is the optimal tool for quantitative assessment of brain morphological and cellular changes induced by neurotoxic lesions or treatment interventions.
Katrine Fabricius +3 more
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Image Analysis and Stereology, 2011 End-stage renal disease (ESRD) has emerged as a major health issue for Australian Aborigines. This phenomenon is paralleled in other populations that have adopted a Westernised lifestyle, including African Americans.
Kelli J Johnson +3 more
doaj +5 more sources
Melatonin and omega-3 neuroprotection in prenatal rat spinal cord exposed to 900 MHz electromagnetic field [PDF]
Biomolecules & BiomedicineThe electromagnetic field (EMF) emitted by electronic devices induces pathological changes in tissues, adversely affecting embryonic and pubertal development.
Ömür Gülsüm Deniz +2 more
doaj +2 more sources
Does the physical disector method provide an accurate estimation of sensory neuron number in rat dorsal root ganglia? [PDF]
Journal of Neuroscience Methods, 2009 The physical disector is a method of choice for estimating unbiased neuron numbers; nevertheless, calibration is needed to evaluate each counting method. The validity of this method can be assessed by comparing the estimated cell number with the true number determined by a direct counting method in serial sections.
Rudolf Kraftsik, Thierry Kuntzer
exaly +5 more sources
Practicable methods for histological section thickness measurement in quantitative stereological analyses. [PDF]
PLoS ONE, 2018 The accuracy of quantitative stereological analysis tools such as the (physical) disector method substantially depends on the precise determination of the thickness of the analyzed histological sections.
Cyrill Matenaers +4 more
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Stereological estimates of nuclear number in human ventricular cardiomyocytes before and after birth obtained using physical disectors [PDF]
Journal of Anatomy, 1997 Design‐based stereology is employed to estimate total numbers of myocyte nuclei and mean myocyte volume per nucleus in ventricles of fetal and early postnatal human hearts. Organs were collected postmortem from subjects varying in age from 16 gestational wk to 40 postnatal wk.
T M, Mayhew +3 more
openaire +2 more sources
Image Analysis and Stereology, 2011 Two methods for the estimation of number per unit volume NV of spherical particles are discussed: the (physical) disector (Sterio, 1984) and Saltykov's estimator (Saltykov, 1950; Fullman, 1953).
Ashot Davtian +3 more
doaj +1 more source
Cell counting in human endobronchial biopsies--disagreement of 2D versus 3D morphometry. [PDF]
PLoS ONE, 2014 QUESTION: Inflammatory cell numbers are important endpoints in clinical studies relying on endobronchial biopsies. Assumption-based bidimensional (2D) counting methods are widely used, although theoretically design-based stereologic three-dimensional (3D)
Vlad A Bratu +7 more
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Canadian Journal of Kidney Health and Disease, 2014 Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) are a polymorphic group of clinical disorders comprising the major cause of renal failure in children. Included within CAKUT is a wide spectrum of developmental malformations ranging from renal
Michel G Arsenault +6 more
doaj +1 more source
Image Analysis and Stereology, 2011 The antennal lobe of the worker honey bee has been used as a model system to address the origins of structural plasticity in the central nervous system.
Sheena M Brown +2 more
doaj +1 more source