Results 51 to 60 of about 215,358 (303)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The influence of a yoga exercise program for young adults with intellectual disabilities
International Journal of Yoga, 2012 Background: Individuals with intellectual disabilities (ID) have an increased risk of obesity and are significantly less likely to engage in physical activity compared to their nondisabled peers.
Brent L Hawkins +3 more
doaj +1 more source
A New Way to Measure Physical Exertion: The Compensatory Reserve [PDF]
, 2017 During periods of physiological stress, such as hemorrhage, the body is able to deploy multiple mechanism of compensation such as changes in heart rate and vascular tone.
Fritzsche, Sarah +2 more
core +1 more source
The Heart Cases in Workmen’s Compensation: An Analysis and Suggested Solution [PDF]
, 1967 It is one of the great tragedies of the workmen\u27s compensation story that almost all courts, in their perfectly justifiable search for a legal barrier that would keep compensation heart liability from getting out of hand, have seized upon the wrong ...
Larson, Arthur
core +3 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Trakia Journal of SciencesPhysical education and sports lecturers should evaluate the impact of physical exercises proposed for implementation in the home environment. The use of self-report scales for the degree of physical exertion is a valuable tool for ...
P. Angelova, D. Ignatova
doaj +1 more source
Cyber Buddy is Better than No Buddy: A Test of the Köhler Motivation Effect in Exergames. [PDF]
, 2014 Objective: Although exergames are popular, few people take advantage of the potential of group dynamics to motivate play (and achieve associated health bene?ts).
Feltz, Deborah L. +3 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Future user research for exertion games [PDF]
, 2012 Exertion is gaining currency in digital game design. Exertion games promise increased athletic performance and hence health benefits. They also offer enhanced engagement due to the coupling of physical engagement with digital gameplay.
Berthouze, N +4 more
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source