Results 71 to 80 of about 91,865 (295)

Towards mobile collaborative exergaming

, 2009
Paper presented at the 2nd International Conference on Advances in Human-oriented and Personalized Mechanisms, Technologies, and Services (CENTRIC2009), September 20-25, 2009, Porto, PortugalToday’s high calorie diets and low physical activity levels ...
Gorgu, Levent, Gregory M. P. O'Hare, O'Hare, G. M. P. (Greg M. P.), O'Grady, Michael J., Levent Gorgu, O\u27Grady, Michael J., O\u27Hare, G. M. P. (Greg M. P.), Michael J. O'Grady   +7 more
core   +1 more source

The Impact of Cognitive and Physical Effort Exertion on Physical Effort Decisions: A Pilot Experiment [PDF]

, 2021
Research suggests that cognitive fatigue has a negative impact on physical activity participation. However, the mechanisms underlying this effect are yet unclear.
Geurts, Sabine A.E., Michiel A. J. Kompier, Sabine Geurts, Masud Husain, Debby G. J. Beckers, Beckers, Debby G.J., Sven van As, van As, Sven, Kompier, Michiel A.J., Sabine A. E. Geurts, Harm Veling, Husain, Masud, Veling, Harm   +12 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Comparison of different ways of expressing creatine kinase concentration of soccer players during a competitive season

Motriz: Revista de Educacao Fisica
The aim of this study was to analyze the responses of creatine kinase [CK] expressed in different forms to the training load of professional soccer players during a competitive season. Twelve players (age, 24 ± 4 years) participated in the study.
Daniel Barbosa Coelho, Christian Emmanuel Torres Cabido, Victor Augusto Lemos Ciminelli, Leonardo Gomes Martins Coelho, Lenice Kapes Becker, Emerson Cruz de Oliveira, Emerson Rodrigues Pereira, João Carlos Bouzas Marins, Emerson Silami Garcia   +8 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Physical exercise at the workplace reduces perceived physical exertion during healthcare work:cluster randomized controlled trial

, 2015
BACKGROUND: High physical exertion during work is a risk factor for musculoskeletal pain and long-term sickness absence. Physical exertion (RPE) reflects the balance between physical work demands and physical capacity of the individual.
Aagaard, Per; id_orcid, Jakobsen, Markus Due, Jay, Kenneth, Aagaard, Per, Andersen, Lars L., Sundstrup, Emil, Andersen, Lars L, Brandt, Mikkel   +7 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Cardiohemodinamic condition and physical working capacity in sportsmen with small anomalies of heart development

Zaporožskij Medicinskij Žurnal, 2015
Aim. Cardiohemodinamic changes in sportsmen with small anomalies of heart development during performance of physical exertion and their influence on physical working capacity is an actual problem of modern sports medicine. Methods and results. For the
O. B. Nekhanevich
doaj   +1 more source

The Association Between Internal and External Measures of Training Load in Batsmen and Medium-Fast Bowlers During Net-Based Cricket Training. [PDF]

, 2017
PURPOSE - To examine the relationship between session Rating of Perceived Exertion (sRPE) and measures of internal and external training load (TL) within cricket batsmen and medium-fast bowlers during net-based training sessions.
Dascombe, Ben (R21089), Duffield, Rob, Vickery, W, Vickery, Will, Dascombe, Ben, Dascombe, B, Duffield, R   +6 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source