Results 61 to 70 of about 5,604,467 (279)

Cerebral carbohydrate cost of physical exertion in humans [PDF]

open access: yesAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2004
Above a certain level of cerebral activation the brain increases its uptake of glucose more than that of O2, i.e., the cerebral metabolic ratio of O2/(glucose + [Formula: see text] lactate) decreases. This study quantified such surplus brain uptake of carbohydrate relative to O2 in eight healthy males who performed exhaustive exercise.
Dalsgaard, Mads K   +5 more
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Central and peripheral manipulations of perceived exertion and endurance performance [PDF]

open access: yes, 2014
Perception of effort, defined as “the conscious sensation of hard, heavy and strenuous exercise”, is known to regulate endurance performance and human behaviour.
Pageaux, Benjamin
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The influence of a yoga exercise program for young adults with intellectual disabilities

open access: yesInternational Journal of Yoga, 2012
Background: Individuals with intellectual disabilities (ID) have an increased risk of obesity and are significantly less likely to engage in physical activity compared to their nondisabled peers.
Brent L Hawkins   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

APPLYING THE BORG'S RATINGS OF PERCEIVED EXERTION SCALE TO ASSESS MOTOR DEVELOPMENT IN ONLINE UNIVERSITY LEARNING

open access: yesTrakia Journal of Sciences
Physical education and sports lecturers should evaluate the impact of physical exercises proposed for implementation in the home environment. The use of self-report scales for the degree of physical exertion is a valuable tool for ...
P. Angelova, D. Ignatova
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Factors affecting perceived exertion and task duration during intermittent isometric fatiguing exercise and their implications for rehabilitation following knee surgery [PDF]

open access: yes, 2012
It has been theorised that self-perception is integral to the regulation of exercise and production of an optimal performance. This concept has not been examined in an anterior cruciate ligament (ACL) reconstructed population where the consequences of ...
Shepherd, J
core  

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