Results 81 to 90 of about 5,371,306 (383)

Physical fitness of children and adolescents with moderate to severe intellectual disabilities

Disability and Rehabilitation, 2019
Background: Low levels of physical fitness are associated with low physical and mental health. The aims of this study were to assess the health-related physical fitness of children with intellectual disability (ID), and study the association of physical ...
M. Wouters, H. Evenhuis, T. Hilgenkamp
semanticscholar   +1 more source

Systematic Review of Changes and Recovery in Physical Function and Fitness After Severe Acute Respiratory Syndrome–Related Coronavirus Infection: Implications for COVID-19 Rehabilitation

Physical Therapy, 2020
Objectives 1) Compare physical function and fitness outcomes in people infected with SARS-CoV to healthy controls; 2) quantify the recovery of physical function and fitness following SARS-CoV infection; 3) determine the effects of exercise following SARS-
Scott Rooney, Amy Webster, L. Paul
semanticscholar   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Endurance exercise upregulates mtp expression in aged Drosophila to ameliorate age‐related diastolic dysfunction and extend lifespan

Physiological Reports
Diastolic dysfunction is a major cardiac dysfunction, and an important predisposing factor is age. Although exercise training is often used for the prevention and treatment of cardiovascular disease nowadays, little is currently known about whether ...
Tianhang Peng, Meng Ding, Hanhui Yan, Ping Zhang, Rui Tian, Yin Guo, Lan Zheng   +6 more
doaj   +1 more source

Endurance exercise resistance to lipotoxic cardiomyopathy is associated with cardiac NAD+/dSIR2/PGC-1α pathway activation in old Drosophila

Biology Open, 2019
Lipotoxic cardiomyopathy is caused by excessive lipid accumulation in myocardial cells and it is a form of cardiac dysfunction. Cardiac PGC-1α overexpression prevents lipotoxic cardiomyopathy induced by a high-fat diet (HFD).
Deng-Tai Wen, Lan Zheng, Jin-xiu Li, Dan Cheng, Yang Liu, Kai Lu, Wen-qi Hou   +6 more
doaj   +1 more source

Developmental change in motor competence : a latent growth curve analysis [PDF]

, 2019
Background: The development of childhood motor competence demonstrates a high degree of inter-individual variation. Some children's competence levels increase whilst others' competence levels remain unchanged or even decrease over time.
Bardid, Farid, Coppens, Eline, D'Hondt, Eva, Deconinck, Frederik, Haerens, Leen, Lenoir, Matthieu, Stodden, David   +6 more
core   +3 more sources

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Does living in urban or rural settings affect aspects of physical fitness in children? An allometric approach. [PDF]

, 2005
The aim of this study was to investigate physical fitness in relation to fatness in urban and rural Greek children by means of allometric scaling. METHODS: The sample consisted of 360 (189 urban and 171 rural; age 12.3+/-0.42 years) boys and 247 (125 ...
Kellis, S., Koutedakis, Yiannis, Tsigilis, N., Tsimeas, P.D., Tsiokanos, A.L.   +4 more
core   +2 more sources

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Prevalence of physical fitness in Chinese school-aged children: Findings from the 2016 Physical Activity and Fitness in China—The Youth Study

Journal of Sport and Health Science, 2017
Purpose: This study was to present the 2016 prevalence estimates of Chinese school-aged children meeting physical fitness standards and to examine differences by sex and residence locales in children who did not meet fitness standards.
Zheng Zhu, Yang Yang, Zhenxing Kong, Yimin Zhang, Jie Zhuang   +4 more
doaj   +1 more source