Results 71 to 80 of about 295,009 (312)

Exercise modality–dependent non-hypertrophic anabolic adaptations in skeletal muscle of rats with type 2 diabetes

open access: yesFrontiers in Physiology
BackgroundType 2 diabetes mellitus (T2DM) is frequently accompanied by progressive skeletal muscle loss and dysfunction, commonly referred to as diabetic sarcopenia.
Yi-dan Zhang   +8 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Changes in Fitness, physical activity, fatness, and screen time: A longitudinal study in children and adolescents

open access: yes, 2009
*_Objective:_* To analyze whether changes in Physical Activity Index (PAI), sedentary time (ST; TV and PC use), and Body Mass Index (BMI) made a significant contribution to longitudinal changes in Physical Fitness (PF) of children and adolescents ...
Clarice Martins   +7 more
core  

Effects of ageing in physical fitness [PDF]

open access: yes, 2016
Ageing is a natural and inevitable process with degenerative changes in most of the physical, physiological and psychological functions. Furthermore, the ageing process has an impact on the physical of elderly people.
Chiva-Bartoll, Oscar   +3 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Self-assessment of physical fitness in adolescents

open access: yes, 2017
Background: Physical fitness is an important indicator of the current and future health condition in adolescents. In comparison with institutional testing, self-assessment of physical fitness offers a number of benefits, including minimization or ...
Dušková Lada   +4 more
core   +1 more source

The Impact of Sport-Specific Practice on Health-Related Physical Fitness Components in Young Water Polo and Volleyball Athletes

open access: yesApplied Sciences
Physical fitness (PF) has been identified as a critical health marker in youth and is significantly influenced by environmental factors, such as the specificity of training involved in different sports.
Francesco Sgrò   +5 more
doaj   +1 more source

Endurance exercise resistance to lipotoxic cardiomyopathy is associated with cardiac NAD+/dSIR2/PGC-1α pathway activation in old Drosophila

open access: yesBiology Open, 2019
Lipotoxic cardiomyopathy is caused by excessive lipid accumulation in myocardial cells and it is a form of cardiac dysfunction. Cardiac PGC-1α overexpression prevents lipotoxic cardiomyopathy induced by a high-fat diet (HFD).
Deng-Tai Wen   +6 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Influence of surgery and rehabilitation conditioning on psychophysiological fitness

open access: yes, 2008
The purpose of this study was to assess changes in psychophysiological fitness following reconstructive knee surgery and early phase (2.5 months) physical rehabilitation. Nine patients (7 male, 2 female; mean age, 29.9 years) electing to undergo anterior
Bailey, A   +9 more
core  

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