Results 111 to 120 of about 59,690 (299)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Determining Ribosome Translational Status by Ribo-ELISA

open access: yesBio-Protocol, 2018
The Ribo-ELISA was originally developed to elucidate the basis for the ribopuromycylation method (RPM)-based detection of ribosome bound nascent chains. The Ribo-ELISA enables characterization of the translational status of ribosomes, and can be applied ...
Amandine Bastide   +2 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Spatiotemporal Fractionation in Radiotherapy [PDF]

open access: yes
In current clinical practice, radiotherapy treatments are often fractionated, i.e. the total radiation dose is equally divided into small fractions to be delivered daily over a period of few days or weeks.
Torelli, Nathan
core   +1 more source

Tracing Polymerization in Calcium Silicate Hydrates Using Si Isotopic Fractionation [PDF]

open access: yes, 2018
Silicate-chains polymerization is a crucial process in calcium silicate hydrate minerals, with large relevance for improving the durability and reducing the environmental impact of cement-based materials.
Ayuela, Andrés   +12 more
core   +1 more source

Computational fluid dynamic analysis of temperature distribution on the integrated pyrolysis–fractionation process of used oil

open access: yesResults in Engineering
Used oil, particularly from motor vehicles and industrial machinery, is composed of several harmful contaminants capable of causing serious risks to the environment and human health.
Maya Ramadianti Musadi   +6 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park   +7 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Does density fractionation of SOC represent chemically different carbon pools? [PDF]

open access: yes, 2012
Organic matter stabilization is thought to be a process of physical protection and chemical recalcitrance. The determination of recalcitrant soil organic carbon (SOC) often relies on operational definitions provided by various fractionation techniques ...
Saavedra, Ana Karina   +6 more
core  

Home - About - Disclaimer - Privacy