Results 111 to 120 of about 5,655,227 (298)
The Deuterium Fractionation of NH3 in Massive Star-forming Regions
Deuteration is sensitive to environmental conditions in star-forming regions. To investigate NH _2 D chemistry, we compared the spatial distribution of ortho-NH _2 D ${1}_{11}^{s}-{1}_{01}^{a}$ , NH _3 (1,1), and NH _3 (2,2) in 12 late-stage massive star-
Yuqiang Li +8 more
doaj +1 more source
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Factors that impact on participation in physical education [PDF]
Physical education uses or employs what modern society recognises as sport and other similar activities to deliver curricular content that requires students to be physically active. However, not all students are committed to participate.
Forsyth, Stuart +3 more
core +2 more sources
White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian +8 more
wiley +1 more source
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera +20 more
wiley +1 more source
In the context of the White Book of Physical and Rehabilitation Medicine (PRM) in Europe, this paper deals with the fundamentals of PRM from a physiological perspective, looking at the human mechanisms both physical and behavioral which are at the base ...
Ceravolo Maria Gabriella +1 more
core +1 more source
Used oil, particularly from motor vehicles and industrial machinery, is composed of several harmful contaminants capable of causing serious risks to the environment and human health.
Maya Ramadianti Musadi +6 more
doaj +1 more source
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source
A novel binary particle fractionation technique
An interesting development towards a robust particle fractionator is presented. Typically acoustic fractionators rely on time of flight in a constant acoustic field to separate different populations .
Harris, Nick +3 more
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