Results 131 to 140 of about 2,296,541 (319)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

THE EFFECT OF PHYSICAL ACTIVITY ON PULMONARY FUNCTION IN PATIENTS WITH PECTUS EXCAVATUM

, 2020
Background. The aim of this study was to determine the impact of the level of physical activity on pulmonary function in patients with pectus excavatum. Material and methods.
Mikuľák, Martin, Peresta, Yuriy, Yuriy Peresta, Wioletta Mikuľáková, Jakub Čuj, Lucia Kendrová, Martin Mikuľák, Stanislava Kuželová, Miloslav Gajdoš, Kendrová, Lucia, Gajdoš, Miloslav, Kuželová, Stanislava, Mikuľáková, Wioletta, Čuj, Jakub   +13 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Promoting physical activity for elders with compromised function: the Lifestyle Interventions and Independence for Elders (LIFE) Study physical activity intervention

, 2013
W Jack Rejeski,1 Robert Axtell,2 Roger Fielding,3 Jeffrey Katula,1 Abby C King,4 Todd M Manini,5 Anthony P Marsh,1 Marco Pahor,5 Alvito Rego,6 Catrine Tudor-Locke,7 Mark Newman,8 Michael P Walkup,9 Michael E Miller9  On behalf of the LIFE Study ...
Pahor M, Tudor-Locke C, Fielding R, Newman M, Manini TM, Miller ME, Walkup MP, Rego A, Axtell R, King AC, LIFE Study Investigator Group, Rejeski WJ, Katula J, Marsh AP   +13 more
core  

Evaluating the efficacy of leading large language models in the Japanese national dental hygienist examination: A comparative analysis of ChatGPT, Bard, and Bing Chat

Journal of Dental Sciences
Background/purpose: Large language models (LLMs) such as OpenAI's ChatGPT, Google's Bard, and Microsoft's Bing Chat have shown potential as educational tools in the medical and dental fields.
Shino Yamaguchi, Masaki Morishita, Hikaru Fukuda, Kosuke Muraoka, Taiji Nakamura, Izumi Yoshioka, Inho Soh, Kentaro Ono, Shuji Awano   +8 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Association between breakfast consumption frequency and handgrip strength and standing long jump: a systematic review and meta-analysis

Frontiers in Psychology
Background and aimsOver the past decade, numerous studies investigating the relationship between breakfast consumption frequency and handgrip strength and standing long jump have produced conflicting evidence, leading to uncertainty regarding this ...
Zhongyu Ren, Xiaoping Zhang, Yanqing Wei, Shuai Liu, Bing Cao, Hejin Wang   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The role of physical function and physical activity on cognitive function in the elderly

Global Transitions
The aim of this study is to clarify the role of physical activity level and physical function on cognitive function of the elderly. A nested case–control investigation from a middle-aged and elderly cognitive health cohort was conducted. 103 mild cognitive impairment (MCI) patients were selected for the purpose of the study and matched 1:1 according to
Chengyan Qi, Xianyun Wang, Dajun Li, Huini Ding, Jing Shen, Yuning Jiao, Wangziyan Lu, Yuandi Xi   +7 more
openaire   +2 more sources