Results 51 to 60 of about 5,933,912 (298)
, 2023 Aims: This study aims to identify physical inactivity-related challenges and motives, based on reviews and supplemented by expert interviews with Danish national experts on physical inactivity, providing a general discussion of the subject ultimately ...
Troelsen, Jens +6 more
core +1 more source
Indian Journal of Community MedicineBackground: In a country of 1.3 billion people with cultural and lifestyle diversities, several previous attempts have been made to compile the burden of cardiovascular diseases. 3.2 million people die each year due to physical inactivity. Traditionally,
Preetham M Shenoy, Nanjesh S Kumar
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The Influence of Family Adversities on Longitudinal Changes in Physical Inactivity Among Korean Adolescents During the COVID-19 Pandemic [PDF]
Journal of Preventive Medicine and Public HealthObjectives: Lack of physical activity has a critical effect on the physical and mental health of adolescents. This study examined the influence of family adversities on the longitudinal changes in physical inactivity among adolescents during the ...
Tae Kyoung Lee +7 more
doaj +1 more source
Physical Inactivity and Health
Pakistan BioMedical Journal, 2022 Health is the measure of our body’s efficiency and over-all well-being. Health triangle consisting of physical, social, and mental health is a standard for many health aspects. Physical activity (PA) is any bodily movement that uses energy produced by the skeletal muscles.
openaire +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Estimating the burden of disease attributable to physical inactivity in South Africa in 2000 [PDF]
, 2007 Objectives. \ud \ud To quantify the burden of disease attributable to physical inactivity in persons 15 years or older, by age group and sex, in South Africa for 2000. \ud \ud Design.
Bull, Fiona +21 more
core +1 more source
Physical inactivity: a behavioral disorder in the physical therapist's scope of practice
, 2020 In health, the gold standard is a state of complete physical, mental, and social well-being.1 This state is weakened by physical inactivity, which involves a higher risk of cardiovascular disease,2 hypertension,3 diabetes,2,4 cancer,5 depression,6 and ...
Iversen, MD, Boisgontier, MP
core +1 more source
Association between Physical Inactivity and Academic Record in Korean Adolescents [PDF]
Iranian Journal of Public Health, 2012 Background: The purpose of this study was to investigate the association between physical inactivity and academic record in Korean adolescents.Methods: Adolescent students from the first grade of middle school to the third grade of high school (n=75,066 ...
Wi-Young So, Yi-Soo Shin
doaj +2 more sources