Results 61 to 70 of about 5,933,912 (298)

Nonregular Physical Activity and Handgrip Strength as Indicators of Fatigue and Psychological Distress in Cancer Survivors

Current Oncology
Background: Cancer survivors who do not engage in regular physical activity often experience persistent psychological distress and fatigue, which can significantly impact their quality of life.
Ilaria Pepe, Alessandro Petrelli, Francesco Fischetti, Carla Minoia, Stefania Morsanuto, Livica Talaba, Stefania Cataldi, Gianpiero Greco   +7 more
doaj   +1 more source

Physical Inactivity and Related Barriers: A Study in a Community Dwelling of Older Brazilians

Journal of Aging Research, 2012
This study sought to investigate the prevalence of physical inactivity and related barriers in older Brazilian adults. A cross-sectional, population-based study was conducted, and a stratified random sampling procedure was used.
Sebastião Gobbi, Emerson Sebastião, Camila Bosquiero Papini, Priscila Missaki Nakamura, Américo Valdanha Netto, Lilian Teresa Bucken Gobbi, Eduardo Kokubun   +6 more
doaj   +1 more source

Burden of ischemic heart disease mortality attributable to physical inactivity in Brazil

Revista de Saúde Pública, 2018
OBJECTIVE To analyze if the burden of ischemic heart disease mortality trend attributed to physical inactivity in Brazil differs from the global estimates.
Diego Augusto Santos Silva, Deborah Carvalho Malta, Maria de Fatima Marinho de Souza, Mohsen Naghavi   +3 more
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Associations Between Physical Activity and Inactivity Levels on Physical Function and Sleep Parameters of Older Adults With Frailty Phenotype

, 2023
This study investigated the relationship between physical activity, inactivity, physical function, and sleep in older adults with a frailty phenotype. A total of 184 pre-frail/frail older adults were included.
Vázquez Sánchez, María Ángeles, Casals Vázquez, Cristina, Espinar Toledo, Milagrosa, Ávila Cabeza de Vaca, Laura, Corral Pérez, Juan, García-Agua Soler, Nuria, Mier, Alba, González Mariscal, Andrea María   +7 more
core   +1 more source

Physical inactivity attributable burden of disease on morbidity and mortality across Swiss language regions: a population-based modelling study

Swiss Medical Weekly
  BACKGROUND: Physical inactivity is a major risk factor for noncommunicable diseases, contributing to both substantial morbidity and premature mortality. In Switzerland, the prevalence of physical inactivity varies across language regions.
Lara Güntert, Jan Taeymans, Heiner Baur, Marcus Van Dyck, Nathanael Lutz   +4 more
doaj   +1 more source

Is Physical Inactivity Associated With Musculoskeletal Disorders?

Ağrı - The Journal of The Turkish Society of Algology, 2013
The aim of our study was to determine the relationship between musculoskeletal disorders (MD) and physical activity levels (PAL) in individuals.125 individuals (74 female, 51 male) aged between 20-65 participated in the study. Extended Nordic Musculoskeletal Questionnaire was used to examine MD, International Physical Activity Questionnaire was used to
Uz Tunçay, Selin, Aydin, Gamze
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Physical distancing [is not equal to] physical inactivity

, 2021
During this time of global health crisis, physical distancing, along with mask wearing, has emerged as the sine qua non social practice to protect ourselves and others from COVID-19.
Gustat, Jeanette, Meyer, Stefanie M., Lemon, Stephenie C, Landry, Matthew J., Webster, Collin A.   +4 more
core   +1 more source

Physical inactivity caused economic burden depends on regional cultural differences

, 2019
Physical inactivity is a major risk factor for numerous non-communicable diseases which dominate the overall burden of disease in Switzerland. We aimed to estimate the burden attributable to adult physical inactivity in Switzerland and its three ...
Probst-Hensch, Nicole, Mattli, Renato; https://orcid.org/, Schmidt-Trucksäss, Arno; https://orcid.org/, Schwenkglenks, Matthias, Wieser, Simon   +4 more
core   +2 more sources