Results 51 to 60 of about 446,185 (284)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Real-Time Three-Dimensional Tracking of Distant Moving Objects Using Non-Imaging Single-Pixel LiDAR

Remote Sensing
The real-time tracking of moving objects has extensive applications in various domains. Existing tracking methods typically utilize video image processing, but their performance is limited due to the high information throughput and computational ...
Zijun Guo, Zixin He, Runbo Jiang, Zhicai Li, Huiling Chen, Yingjian Wang, Dongfeng Shi   +6 more
doaj   +1 more source

Analysis of Optical Turbulence over the South China Sea Using Balloon-Borne Microthermal Data and ERA5 Data

Remote Sensing, 2022
It is very useful for adaptive optics (AO) systems to have appropriate knowledge of optical turbulence. However, due to the limitations of space and time, it is difficult to obtain turbulence parameters, especially in the far sea area. In this paper, the
Manman Xu, Shiyong Shao, Ningquan Weng, Qing Liu   +3 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Spatial Fluctuations of Optical Turbulence Strength in a Laboratory Turbulence Simulator

Photonics
Controlled turbulence simulators in the laboratory have been extensively employed to investigate turbulence effects on light propagation in the atmosphere, driven by some advanced optical engineering such as remote sensing, energy-delivery systems, and ...
Yanling Li, Haiping Mei, Shuran Ye, Zhiwei Tao, Hanling Deng, Xiaoqing Wu, Ruizhong Rao   +6 more
doaj   +1 more source

New Denoising Method for Lidar Signal by the WT-VMD Joint Algorithm

Sensors, 2022
Light detection and ranging (LIDAR) is an active remote sensing system. Lidar echo signal is non-linear and non-stationary, which is often accompanied by various noises.
Zhenzhu Wang, Hongbo Ding, Bangxin Wang, Dong Liu   +3 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Simulation Analysis of an Atmospheric Turbulence Wavefront Measurement System

Photonics
In this paper, a turbulent wavefront measurement model based on the Hartmann system structure is proposed. The maximum recognizable mode number of different lens units is discussed, and the influence of different lens array arrangements on the accuracy ...
Gangyu Wang, Laian Qin, Yang Li, Yilun Cheng, Xu Jing, Gongye Chen, Zaihong Hou   +6 more
doaj   +1 more source

Analyzing the Effects of a Basin on Atmospheric Environment Relevant to Optical Turbulence

Photonics, 2022
The performance of adaptive optics (AO) systems are highly dependent upon optical turbulence. Thus, it is necessary to have the appropriate knowledge of the spatiotemporal characteristics of optical turbulence strength.
Manman Xu, Liangping Zhou, Shiyong Shao, Ningquan Weng, Qing Liu   +4 more
doaj   +1 more source