Results 71 to 80 of about 14,720,819 (304)

Physical performance and disability in schizophrenia

Schizophrenia Research: Cognition, 2014
Despite 50 years of pharmacological and psychosocial interventions, schizophrenia remains one of the leading causes of disability. Schizophrenia is also a life-shortening illness, caused mainly by poor physical health and its complications. The end result is a considerably reduced lifespan that is marred by reduced levels of independence, with few ...
M. Strassnig, J. Signorile, C. Gonzalez, P.D. Harvey   +3 more
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Newsfronts in Health, Physical Education & Recreation (vol. 4, no. 1)

, 1976
This four-page document is the Newsfronts in Health, Physical Education & Recreation (vo. 4, no. 1) newsletter published by the Division of Health, Physical Education and Recreation at Springfield College. It is believed that the newsletter was published
School of Physical Education, Performance, and Sport Leadership; School of Health, Physical Education and Recreation;
core  

Diurnal cortisol patterns are associated with physical performance in the Caerphilly Prospective Study. [PDF]

, 2011
BACKGROUND: Cross-sectional studies have suggested that elevated cortisol is associated with worse physical performance, a surrogate of ageing. We examined the relationship between repeat cortisol measures over 20 years and physical performance in later ...
Y. Ben-Shlomo, A. Bayer, Bayer, Antony, J. Gallacher, S. Ebrahim, Gallacher, John, Halcyon study team, Halycon study team, D. Kuh, Gardner, Michael P., Hardy, Rebecca, M. P. Gardner, Lightman, Stafford L., Bayer, Antony James, R. Hardy, null null, S. L. Lightman, Ben-Shlomo, Yoav, Kuh, Diana, Ebrahim, Shah, Lightman, Stafford L, Gardner, Michael P, Gallacher, John Edward   +22 more
core   +1 more source

The effect of strength training on muscle cellular stress in prostate cancer patients on ADT

Endocrine Connections, 2016
Background Androgen deprivation therapy (ADT) for prostate cancer (PCa) is associated with several side effects, including loss of muscle mass. Muscle atrophy is associated with reduced mitochondrial function and increased muscle cellular stress that may
T S Nilsen, L Thorsen, C Kirkegaard, I Ugelstad, S D Fosså, T Raastad   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Relationship between alcohol hangover and physical endurance performance: Walking the Samaria Gorge [PDF]

, 2019
Alcohol hangover is a potentially debilitating state. Several studies have demonstrated that it does not seem to impair strength or short-term endurance, but its effects on continuous exercise performance/long-term endurance have never been investigated.
Stock, Ann Kathrin, Darren Kruisselbrink, Verster, Joris C, Stock, Ann-Kathrin, Kruisselbrink, Darren, Alford, Chris, Ann-Kathrin Stock, Chris Alford, Joris C Verster, Aikaterini Anogeianaki, Anogeianaki, Aikaterini   +10 more
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

The association between mobility and a cognitive measure of attention and processing speed in middle-aged adults: a cross-sectional study

Scientific Reports
Mobility and cognitive functions are closely linked in old age. Although a relationship between mobility and cognitive function has also been demonstrated in midlife, it has not been tested under conditions that might reflect real-life locomotion.
Uriah Turkel, Roee Hayek, Yaniv Nudelman, Itai Gutman, Shmuel Springer   +4 more
doaj   +1 more source

Vitamin C and E supplementation does not affect heat shock proteins or endogenous antioxidants in trained skeletal muscles during 12 weeks of strength training

BMC Nutrition, 2017
Background Supplementation with large doses of antioxidants, such as vitamin C and E, has been shown to blunt some adaptations to endurance training.
K. T. Cumming, T. Raastad, A. Sørstrøm, M. P. Paronetto, N. Mercatelli, I. Ugelstad, D. Caporossi, G. Paulsen   +7 more
doaj   +1 more source