Results 101 to 110 of about 13,429,743 (301)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Developing an integrated smart model for the sustainable organization of residential complexes with an emphasis on the physical structure and the environment (Case study: Dogonbadan city) [PDF]

اکولوژی انسانی
Cities, as the primary hubs of human and economic activities, play a vital role in achieving sustainable development. However, rapid urbanization, land scarcity, increasing housing demand, and environmental challenges necessitate a re-evaluation of urban
Fatemeh Gorjipour, Zarir Salehpour Sarvuk, Ali Aram, Abdolhosein Paknejadi   +3 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

KUALITAS FISIK DAGING DADA DAN PAHA BROILER YANG DIRENDAM DALAM LARUTAN DAUN SALAM (SYZYGIUM POLYANTHUM)

Jurnal Ilmiah Peternakan Terpadu, 2018
The objectives of the study were (1) to know there was or no interaction between soaking time in bay leaf and type of carcass to the physical quality of broiler meat; (2) To know the duration of optimum immersion for the physical quality of the muscles ...
Dian Septinova, Madi Hartono, Purnama Edy Santosa, Siti Hartika Sari   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Introduction to Security & Quality Improvement in Complex Cyber-Physical Systems Engineering

, 2019
The goal of providing Complex Cyber-Physical Systems (C-CPSs) more efficiently and faster requires improvements of engineering process quality for ensuring high quality of the developed engineering artifacts. Furthermore, information security must be a
Weippl, Edgar, Lüder, Arndt, Biffl, Stefan, Eckhart, Matthias   +3 more
core   +4 more sources

Physico-chemical Characterization of Tofu By-Product Silage Supplemented with Fine Rice Bran and Chestnut Tannin as Silage Additives

Jurnal Nutrisi Ternak Tropis
This study seeks to evaluate the physico-chemical properties of tofu waste silage with the inclusion of refined rice bran and chestnut tannins as additives.
Sadarman Sadarman, Rakhmad Perkasa Harahap, Amirul Faiz Mohd Azmi, Dewi Febrina, Rahmi Febriyanti, Gholib, Yunilas, Novia Qomariyah, Rizki Amalia Nurfitriani, Fitrah Khairi   +9 more
doaj   +1 more source