Results 111 to 120 of about 13,429,743 (301)

Methods of evaluation of flexibility of women of 30-45 years in the process of employments by physical exercises [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2012
Directions of determination and estimation of flexibility are considered for the women of mature age. In an experiment 40 women took part in age 35-40.
Sorokina S.A.
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Physical and Chemical Water Quality of Ilam Water Treatment Plant [PDF]

Water usually has some dissolved elements such as solids and gasses. Existences of some elements in water are necessary for human health, but deficiency of many them can cause problems.
تردست, علی, عمارلوئی, علی, مظلومی, سجاد, نوروزی, مهدی, کرمی تبار, یزدان, فضل زاده دویل, مهدی, دهقانی, محمدهادی   +6 more
core  

Physical fitness, physical activity, psychosocial status and quality of life of adolescent siblings of neurologically disabled children

, 2018
Background: This study aims to compare physical fitness, physical activity, the psychosocial state and the quality of life of adolescents who have disabled siblings with the adolescents who have healthy siblings.
Topcu, Zehra Guchan, Celik, Elcin Mamak, Daskapan, Arzu   +2 more
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

White book on physical and rehabilitation medicine (PRM) in Europe. Chapter 5.The PRM organizations in Europe: Structure and activities

, 2018
In the context of the White Book of Physical and Rehabilitation Medicine (PRM) in Europe, this paper addresses the structure, organization and activities of PRM bodies in Europe.
Ceravolo Maria Gabriella, European Physical and Rehabilitation Medicine Bodies Alliance   +1 more
core   +1 more source

Mathematical modeling and optimization of pasteurization for the internal pressure and physical quality of canned beer. [PDF]

Heliyon, 2023
Thongon R, Netramai S, Kijchavengkul T, Yaijam G, Debhakam R.   +4 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source