Results 71 to 80 of about 428,539 (263)

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Advances in neuromodulation for treatment of dystonia

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
Dystonia is a group of movement disorders characterized by continuous or intermittent muscle contraction, causing abnormal movements and/or repetitive postures. It has the characteristics of diverse causes and complex clinical symptoms.
LIANG Nan   +3 more
doaj   +1 more source

A scoping review on hyposalivation associated with systemic conditions: the role of physical stimulation in the treatment approaches. [PDF]

open access: yesBMC Oral Health, 2023
Melo JLMA   +6 more
europepmc   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Combined effect of micro-osteoperforation and vibration on interleukin-1B, receptor activator of nuclear factor kappa-B ligand, C-C motif chemokine ligand 2, and tumor necrosis factor-alpha in orthodontic patients: A parallel-design randomized clinical trial

open access: yesDental Research Journal
Background: Bone remodeling is essential for orthodontic tooth movement. Techniques such as micro-osteoperforation (MOP) and vibration have been introduced to accelerate treatment by stimulating biological responses.
Elahe Gholamrezayi   +3 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

FES Training in Aging: interim results show statistically significant improvements in mobility and muscle fiber size

open access: yesEuropean Journal of Translational Myology, 2012
Aging is a multifactorial process that is characterized by decline in muscle mass and performance. Several factors, including reduced exercise, poor nutrition and modified hormonal metabolism, are responsible for changes in the rates of protein synthesis
Helmut Kern   +14 more
doaj   +1 more source

Associations of Sleep and Shift Work With Osteoarthritis Risk

open access: yesArthritis Care &Research, EarlyView.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik   +5 more
wiley   +1 more source

Differential Effects of Sustained Manual Pressure Stimulation According to Site of Action

open access: yesFrontiers in Neuroscience, 2019
Sustained pressure stimulation of the body surface has been used in several physiotherapeutic techniques, such as reflex locomotion therapy. Clinical observations of global motor responses and subsequent motor behavioral changes after stimulation in ...
Pavel Hok   +12 more
doaj   +1 more source

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