Results 61 to 70 of about 6,894,347 (240)

Use of Surface EMG in Clinical Rehabilitation of Individuals With SCI: Barriers and Future Considerations

Frontiers in Neurology, 2020
Surface electromyography (sEMG) is a widely used technology in rehabilitation research and provides quantifiable information on the myoelectric output of a muscle.
Rakesh Pilkar, Rakesh Pilkar, Kamyar Momeni, Kamyar Momeni, Arvind Ramanujam, Manikandan Ravi, Erica Garbarini, Gail F. Forrest, Gail F. Forrest, Gail F. Forrest   +9 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Electrical stimulation counteracts muscle atrophy associated with aging in humans

European Journal of Translational Myology, 2013
Functional and structural muscle decline is a major problem during aging. Our goal was to improve in old subjects quadriceps m. force and mobility functional performances (stair test, chair rise test, timed up and go test) with neuromuscular electrical ...
Helmut Kern, Stefan Loefler, Samantha Burggraf, Hannah Fruhmann, Jan Cvecka, Milan Sedliak, Laura Barberi, Manuela De Rossi, Antonio Musarò, Ugo Carraro, Simone Mosole, Sandra Zampieri   +11 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Uses of Electrical Stimulation

, 2001
47 p.I became interested in physical therapy and especially electric stimulation during my senior year in high school. In a varsity football game I sustained an injury to my right knee, which caused my kneecap to become dislocated.
Zielaskowski, Brad
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

The effect of sensory stimulation on quality of life of the elderly and their self-efficacy for coping with the fear of falling

Iranian Journal of Nursing and Midwifery Research, 2020
Background: Aging causes major changes that affect the performance of all senses, and as a result, a critical change in the quality of life is expected.
Alehe Seyyedrasooli, Morteza Ghojazadehm, Sakineh Goljaryan, Mohammad-Salar Hosseini, Mahdieh Esmaeilnezhad   +4 more
doaj   +1 more source

Stimulation-induced changes in STN power.

, 2023
(A) Group-averaged time-frequency spectrum (not normalized) aligned to onset of stimulation (after ramping). The dotted box indicates STN beta power after stimulation onset. For statistical tests of changes in different frequency bands, see S3 Table. (B)
Muthuraman Muthuraman (328846), Rafal Bogacz (307953), Sergiu Groppa (3590291), Huiling Tan (500089), Peter Brown (209993), Manuel Bange (16007091), Alek Pogosyan (500091), Martin Glaser (1395892), Damian M. Herz (16007088), Gabriel Gonzalez-Escamilla (6286490), Miriam Auer (16007094)   +10 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Differential brain reorganization in chronic cervical spinal cord injury and its relation to motor versus sensory impairments: a preliminary investigation

Scientific Reports
Spinal cord injury (SCI) disrupts the communication between the brain and the rest of the body, triggering widespread spinal and supraspinal changes resulting in a cascade of functional impairments.
Nabila Brihmat, Soha Saleh, Fan Zhang, Janelle Carnahan, Mehmed B. Bayram, Guang H. Yue, Gail F. Forrest   +6 more
doaj   +1 more source