Results 41 to 50 of about 429,154 (262)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Modulation of interhemispheric inhibition and motor learning by different intensities of bilateral transcranial direct current stimulation in healthy adults

Scientific Reports
Interhemispheric inhibition (IHI) plays a crucial role in performing unilateral hand movements. Transcranial direct current stimulation (tDCS) has been shown to modulate IHI and enhance motor learning, but the most effective stimulation intensity remains
Thatchaya Prathum, Julien Dauguet, Irin Apiworajirawit, Benchaporn Aneksan, Siriwan Hoisan, Arruck Tragangoon, Vorasith Siripornpanich, Wanalee Klomjai   +7 more
doaj   +1 more source

Electrostimulation in sports and rehabilitation

European Journal of Translational Myology, 2011
The known effects of Neuromuscular Electrical Stimulation (NMES) in Sports and Physical Medicine and Rehabilitation are presented in a review of literature.
Helmut Kern
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Electrical stimulation (ES) counteracts muscle decline in seniors

Frontiers in Aging Neuroscience, 2014
The loss in muscle mass coupled with a decrease in specific force and shift in fiber composition are all marks of aging. Training and regular exercise attenuate the signs of sarcopenia. However, pathologic conditions limit the ability to perform physical
Helmut eKern, Laura eBarberi, Stefan eLoefler, Simona eSbardella, Samantha eBurgraff, Hannan eFruhmann, Ugo eCarraro, Simone eMosole, Nejc eSarabon, Michael eVogelauer, Winfried eMayer, Matthias eKrenn, Jan eCvecka, Vanina eRomanello, Laura ePietrangelo, Feliciano eProtasi, Marco eSandri, Sandra eZampieri, Antonio eMusarò   +18 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

eScience Gateway Stimulating Collaboration in Rock Physics and Volcanology [PDF]

2014 IEEE 10th International Conference on e-Science, 2014
Earth scientist observe many facets of the planet's crust and integrate their resulting data to better understand the processes at work. We report on a new data-intensive science gateway designed to bring rock physicists and volcanologists into a collaborative framework that enables them to accelerate their research and integrate well with other Earth ...
Rosa Filgueira, Malcolm P. Atkinson 0001, Andrew Bell, Ian G. Main, Steve Boon, Christopher Kilburn, Philip Meredith   +6 more
openaire   +1 more source

Translational Myology for Physical Medicine and Rehabilitation: the evidence based approach

European Journal of Translational Myology, 2013
Not ...
Helmut Kern
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source