Results 41 to 50 of about 11,574,669 (365)

Stability of Naked Nucleic Acids under Physical Treatment and Powder Formation: Suitability for Development as Dry Powder Formulations for Inhalation

Pharmaceutics, 2023
A number of functional nucleic acids, including plasmid DNA (pDNA) and small interfering RNA (siRNA), have been attracting increasing attention as new therapeutic modalities worldwide.
Tomoyuki Okuda, Maki Okazaki, Akihiko Hayano, Hirokazu Okamoto   +3 more
doaj   +1 more source

Academic Stress, Physical Activity, Sleep, and Mental Health among Chinese Adolescents

International Journal of Environmental Research and Public Health, 2021
The purpose of this study was to examine the impacts of academic stress on physical activity and sleep, and subsequently their impacts on anxiety and depression.
Xihe Zhu, J. Haegele, Huarong Liu, Fangliang Yu   +3 more
semanticscholar   +1 more source

Evaluation of the Effect of Dopamine D2 Receptor Antagonist on the Spermatogenesis Process in Rats Under Physical or Psychological Stress and Their Offspring

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2020
Background and Objectives: Stress disrupts the neurotransmitter release and reproduction. Dopamine (D) is one of the most important neurotransmitters, and its receptor (D2R) has been identified in testis. The use of effective drugs on reproductive system
Shahla Amiri, Farrin Babaei-Balderlou, Gholamreza Najafi   +2 more
doaj  

Models and Methods to Investigate Acute Stress Responses in Cattle

Animals, 2015
There is a growing appreciation within the livestock industry and throughout society that animal stress is an important issue that must be addressed.
Yi Chen, Ryan Arsenault, Scott Napper, Philip Griebel   +3 more
doaj   +1 more source

Physical relaxation for occupational stress in healthcare workers: A systematic review and network meta‐analysis of randomized controlled trials

Journal of Occupational Health, 2021
Work related stress is a major occupational health problem that is associated with adverse effects on physical and mental health. Healthcare workers are particularly vulnerable in the era of COVID‐19.
Michael Zhang, Brittany Murphy, Abegail Cabanilla, Christina Yidi   +3 more
semanticscholar   +1 more source

Stress - its effects on health and behavior: a guide for practitioners [PDF]

, 2014
KEY POINTS Stress may affect the physical, mental, and social health of an animal. The effect of stressors is individual to the animal concerned and results from the appraisal of the stressor by the animal.
Karagiannis, Christos, Mills, Daniel, Zulch, Helen   +2 more
core   +1 more source

Stress Fractures Caused by Physical Exercise [PDF]

Acta Orthopaedica Scandinavica, 1978
A series of 142 stress fractures caused by sporting activities and physical exercise is presented. 121 fractures occurred in athletes and 21 in non-competitive sportsmen. Distance runners presented with 68 fractures, skiers 12, sprinters 10, orienteering runners 9, vaulters 3, and football-players 3 fractures. Athletes engaged in other events had fewer
S, Orava, J, Puranen, L, Ala-Ketola
openaire   +2 more sources

An Improved Model of Physical and Emotional Social Defeat: Different Effects on Social Behavior and Body Weight of Adolescent Mice by Interaction With Social Support

Frontiers in Psychiatry, 2018
Social stress is a prevalent etiological environmental factor that can affect health, especially during adolescence. Either experiencing or witnessing a traumatic event during adolescence can increase the risk of psychiatric disorders, such as PTSD.
Man Li, Man Li, Man Li, Man Li, Hang Xu, Hang Xu, Weiwen Wang, Weiwen Wang   +7 more
doaj   +1 more source

Interplay between pleiotropy and secondary selection determines rise and fall of mutators in stress response [PDF]

, 2009
Dramatic rise of mutators has been found to accompany adaptation of bacteria in response to many kinds of stress. Two views on the evolutionary origin of this phenomenon emerged: the pleiotropic hypothesis positing that it is a byproduct of environmental
A Giraud, A Sali, AC Shaver, B Li, CS Wylie, DK Klimov, E Dekel, E Denamur, E Denamur, E Shakhnovich, E Shakhnovich, EI Shakhnovich, EI Shakhnovich, EJ Deeds, ES Slechta, Eugene I. Shakhnovich, F Taddei, G Feng, GM Suel, HC Tsui, I Bjedov, I Matic, IN Berezovsky, JAGM de Visser, JB Andre, JD Bloom, JM Raser, JW Drake, KB Zeldovich, KB Zeldovich, KB Zeldovich, KK Yan, KL Huisinga, KP Bjornson, L Lopez-Maury, M Heo, M Wrande, MB Elowitz, MJ Schofield, ML Mendillo, Muyoung Heo, N Rosenfeld, O Tenaillon, O Tenaillon, PD Sniegowski, PD Sniegowski, PJ Gerrish, PL Foster, R Du, RE Lenski, RR Iyer, RS Galhardo, RS Harris, Rustom Antia, S Maslov, S Miyazawa, WA Rosche, WJ Blake   +57 more
core   +5 more sources

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source