Results 61 to 70 of about 8,883,693 (307)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Heel Pain-plantar Fasciitis:Revision 2014 Clinical Practice Guidelines Linked to the International Classification of Functioning, Disability and Health

康复学报, 2019
The Orthopaedic Section of the American Physical Therapy Association(APTA)has an ongoing effort to create evidence-based practice guidelines for orthopaedic physical therapy management of patients with musculoskeletal impairments described in the World ...
The Orthopaedic Section of the American Physical Therapy Association
doaj  

Tampa scale for kinesiophobia in individuals with knee osteoarthritis: a cross-sectional psychometric evaluation using item-level and exploratory factor analyses

Scientific Reports
This study evaluated floor and ceiling (F/C) effects within the Tampa Scale for Kinesiophobia (TSK) and examined item-level correlations with total TSK scores and pain intensity in individuals with knee osteoarthritis (KOA).
Prasert Sakulsriprasert, Tipwadee Bunprajun, Ninwisan Hengsomboon, Pichaya Hengsomboon, Pavinee Harutaichun, Chompunoot Suwanasri, Pinyada Warathanagasame, Chutiporn Thammajaree, Akenarin Chocknakawaro, Nattapa Ariyakitsakul   +9 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Hip Pain and Mobility Deficits-Hip Osteoarthritis: Revision 2017 Clinical Practice Guidelines Linked to the International Classification of Functioning, Disability and Health

康复学报, 2019
The Orthopaedic Section of the American Physical Therapy Association(APTA)has an ongoing effort to create evidence-based practice guidelines for orthopaedic physical therapy management of patients with musculoskeletal impairments described in the World ...
The Orthopaedic Section of the American Physical Therapy Association
doaj  

Effects of forward shoulder elevation on spinal excursion at three different speeds

Scientific Reports
This study aims to investigate how varying shoulder movement speeds affect spinal mobility to enhance understanding of the trunk’s adaptive response to these perturbations.
Pichaya Hengsomboon, Ninwisan Hengsomboon, Pavinee Harutaichun, Sunee Bovonsunthonchai, Prasert Sakulsriprasert   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Physical therapy: A critique

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 1997
Some forms of physical therapy are used relatively frequently in the treatment of chronic musculoskeletal pain conditions, including the temporomandibular disorders. We found evidence that cold seems to be a useful treatment for postsurgical pain and swelling and that most patients being treated for most chronic musculoskeletal pain seem to do better ...
Faculty of Dentistry, McGill University. Montreal, Quebec, Canada ( host institution ), Feine, Jocelyne S, Widmer, Charles G, Lund, James P   +3 more
openaire   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Forced expiration: a simple technique that acutely increases core muscle contraction in mild chronic non-specific low back pain

Scientific Reports
The abdominal drawing-in maneuver (ADIM) is widely used to activate the transverse abdominis muscle (TrA). However, the ADIM technique might be challenging to understand and perform correctly, causing the compensation of the internal and external oblique
Pathaimas Kingcha, Kanokwan Polsa, Panakorn Sungnak, Pathtarajaree Junsiri, Roongtiwa Vachalathiti, Peemongkon Wattananon   +5 more
doaj   +1 more source