Results 101 to 110 of about 122,542 (308)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The effectiveness of online courses in physician assistant education [PDF]
, 2006 Click on the link below to access the article (may not be free).To examine whether online curricula were appropriate for physician assistant (PA) programs, one PA program piloted an online curriculum for courses in endocrinology and community health ...
Day, David +2 more
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Program Review: Master of Physician Assistant (MPA) [PDF]
, 2021 -
Physician Assistant (PA) +1 more
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Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
White Coat Ceremony program for the students of the Physician Assistant Studies at Springfield College (October 11, 2013) [PDF]
, 2013 This is the White Coat Ceremony program for the students of the Physician Assistant Studies at Springfield College (October 11, 2013). The program lists the participants, the schedule of events, the names from the Class of 2015, and the Physician ...
Springfield College;
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Invitation for the 1997 White Coat Ceremony for the Physician Assistant Studies Program (October 6, 1997) [PDF]
, 1997 This is the invitation for the 1997 White Coat Ceremony for the students in the Physician Assistant Studies Program at Springfield College. Gives the date, October 6, 1997, and directions.For more information on Department of Physician Assistant Studies ...
Springfield College;
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