Results 111 to 120 of about 612,337 (260)

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Physician Assistant department chair survey: factor analysis [PDF]

, 2005
Peer ...
Smith, Barbara S., Muma, Richard D.
core  

Robots in the OR: Hype, Hope, or Holding Pattern in Cholecystectomy?

Technologies
Robotic-assisted cholecystectomy (RAC) is increasingly presented as the next step in minimally invasive biliary surgery, but its added value over laparoscopic cholecystectomy (LC) remains uncertain.
Muhannad Maher Abdin, Michael Connolly, Alden Stockam, Oleg Karaduta   +3 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Invitation for the 1997 White Coat Ceremony for the Physician Assistant Studies Program (October 6, 1997)

, 1997
This is the invitation for the 1997 White Coat Ceremony for the students in the Physician Assistant Studies Program at Springfield College. Gives the date, October 6, 1997, and directions.For more information on Department of Physician Assistant Studies ...
Springfield College;
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

White Coat Ceremony program for the students of the Physician Assistant Studies at Springfield College (October 11, 2013)

, 2013
This is the White Coat Ceremony program for the students of the Physician Assistant Studies at Springfield College (October 11, 2013). The program lists the participants, the schedule of events, the names from the Class of 2015, and the Physician ...
Springfield College;
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Invitation for the 1998 White Coat Ceremony for the Physician Assistant Program (October 3, 1998)

, 1998
This is the invitation for the 1998 White Coat Ceremony for the students in the Physician Assistant Studies Program at Springfield College. Gives the date, October 3, 1998, and directions.For more information on Department of Physician Assistant Studies ...
Springfield College;
core