Results 91 to 100 of about 478,628 (315)

Referral practices of rural primary care physicians for patients with depression [PDF]

, 2001
Plan BThis research characterizes the treatment and referral practices of rural primary care physicians for their patients with depression. A mailed survey was sent to all practicing physicians in rural Jackson County, Wisconsin and surrounding areas ...
Wentz, Meridith K.
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Sociocultural Factors That Potentially Affect the Institution of Prevention and Treatment Strategies for Hepatitis B in Chinese Canadians

Canadian Journal of Gastroenterology, 2009
BACKGROUND: Despite the availability of screening for chronic hepatitis B (CHB) infection and effective treatments now available, many at-risk individuals fail to seek appropriate medical attention.
Harry Wu, Colina Yim, Alex Chan, Michael Ho, Jenny Heathcote   +4 more
doaj   +1 more source

The curious case of extinction of family physicians from the Indian Health System - An open letter to the members of the National Medical Commission: Draft competency-based medical education curriculum regulations 2023 - Complete exclusion of family physicians/family medicine education from the MBBS course curriculum! [PDF]

J Family Med Prim Care, 2023
Kumar R.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Family physicians beliefs and attitudes regarding adult pneumococcal and influenza immunization in Lebanon

, 2011
Background. Influenza and pneumococcal diseases are responsible for more deaths than all other vaccine-preventable diseases combined. Despite all efforts, the vaccination rate is below target.Objectives.
Romani M.H., Hamadeh G.N., Musharrafieh U.M., Lakkis N.A.   +3 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

The Spatial Distribution of Physicians in the United States: A Review of the Literature [PDF]

, 1977
One manifestation of a contemporary concern with equality in the provision of health care services is the growing interest that appears to be developing in the spatial location of medical manpower. There is no evidence that any country has ever achieved,
Butler, J.R.
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

The Influence of Family Physicians Within the South African District Health System: A Cross-Sectional Study [PDF]

, 2018
PURPOSE : Evidence of the influence of family physicians on health care is required to assist managers and policy makers with human resource planning in Africa.
Indiran Govender, Robert J. Mash, Steinberg, Wilhelm Johannes, Esterhuizen, Tonya M., Laurel Baldwin-Ragaven, Baldwin-Ragaven, Laurel, Govender, Indiran, Klaus B. von Pressentin, Wilhelm Johannes Steinberg, Botha, R.P.G. (Roelf Petrus Gerhardus), Tonya M. Esterhuizen, Mash, Robert J., Von Pressentin, Klaus B., Roelf Petrus Gerhardus Botha   +13 more
core   +1 more source