Results 141 to 150 of about 1,473,116 (296)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Get paid more, work more? Lessons from French physicians' labour supply responses to hypothetic fee increases [PDF]

This paper is devoted to the analysis of the General Practitioners' (GPs) labour supply, specifically focusing on the physicians' labour supply responses to higher compensations.
Olivier Chanel, Alain Paraponaris, Christèle Protière, Bruno Ventelou   +3 more
core  

Preoperative risk factors for extended hospital stay: A prospective study in a South African clinic

African Journal of Primary Health Care & Family Medicine
Background: Preoperative assessment clinics play a critical role in identifying, evaluating and mitigating perioperative risks. Despite global data highlighting the importance of preoperative risk factors on surgical outcomes, there remains limited ...
Kuven Naidu, Nabeela Kajee, Jayseelan Naidu, Bilaal Wadee   +3 more
doaj   +1 more source

Additional file 1: of Effect of individualized communication skills training on physiciansâ discussion of clinical trials in oncology: results from a randomized controlled trial

, 2017
SA. Descriptive data of Control Group and Intervention Group results from the COM-ON-rct-Checklist by independent raters. SB. Descriptive data of Feeling of Confidence in 10 domains. (DOCX 22Â kb)
Wuensch, Alexander, Goelz, Tanja, Ihorst, Gabriele, Terris, Darcey, Bertz, Hartmut, Bengel, Juergen, Wirsching, Michael, Fritzsche, Kurt   +7 more
openaire   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Quality medical care for adolescents: adolescents versus physiciansÓ? perception

Portuguese Journal of Pediatrics
Introduction and Objectives: Adolescence is a key developmental period, requiring a distinct clinical approach. Aspects such as communication, confidentiality, and privacy are particularly relevant in adolescence, as indicators of the quality of health care according to the World Health Organization.
Madalena Meira Nisa, Antonio Videira-Silva, Mariana Beatriz Fonseca Mourasup, Sofia Moeda, Sílvia Freira, Helena Fonseca   +5 more
openaire   +2 more sources

MOESM2 of Physiciansâ utilization of microbiologic reports and determinants of their preference to order culture in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia

, 2018
Additional file 2. Initial therapy type, type of change and the reasons for change in hospitalized patients in the internal medicine ward of TASH in 2014, Addis Ababa, Ethiopia.
Alemkere, Getachew, Gilagil, Getu, Gebrehiwot, Teklu, Tilahun, Zelalem, Mengist, Hylemariam   +4 more
openaire   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Additional file 1: of Identifying frailty in primary care: a qualitative description of family physiciansâ gestalt impressions of their older adult patients

, 2018
Interview Guide. Question used for interviewing participants. (DOCX 12Â kb)
Korenvain, Clara, Ida-Maisie Famiyeh, Dunn, Sheila, Whitehead, Cynthia, Rochon, Paula, McCarthy, Lisa   +5 more
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source