Results 121 to 130 of about 3,276,266 (409)
Knowledge about cancer in a group of practicing physicians [PDF]
, 1951 Howard R. Bierman +2 more
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
The Bradshaw Lecture ON HYSTERIA IN SOME OF ITS ASPECTS: Delivered at the Royal College of Physicians, November 4th, 1913 [PDF]
, 1913 Tari-Rae Glynn
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Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
The Harveian Oration ON WILLIAM HARVEY, OBSTETRIC PHYSICIAN AND GYNAECOLOGIST: Delivered before the Royal College of Physicians of London on October 18th, 1921 [PDF]
, 1921 H. R. Spencer
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Molecular Oncology, EarlyView.In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa +14 more
wiley +1 more source
The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Molecular Oncology, EarlyView.Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
wiley +1 more source
INTRAVENOUS INJECTION IN WOUND SHOCK: Abstract of the Oliver-Sharpey Lectures delivered before the Royal College of Physicians on April 30th and May 2nd, 1918 [PDF]
, 1918 William Maddock Bayliss
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Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
BMC NutritionAims/Hypothesis This secondary analysis compared the effect of a vegan to a portion-controlled diet on insulin use and insulin costs in people with type 1 diabetes (T1D). Methods Fifty-eight adults with T1D were randomly assigned to a vegan (n = 29) or a
Hana Kahleova +6 more
doaj +1 more source