Results 11 to 20 of about 839,896 (285)

Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer’s disease

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Effective therapy of Alzheimer’s disease (AD) requires treatment with a combination of drugs that modulate various pathomechanisms contributing to the disease.
Natalia Szałaj, Justyna Godyń, Jakub Jończyk, Anna Pasieka, Dawid Panek, Tomasz Wichur, Krzysztof Więckowski, Paula Zaręba, Marek Bajda, Anja Pislar, Barbara Malawska, Raimon Sabate, Anna Więckowska   +12 more
doaj   +1 more source

Study of pine forest stand structure in the Priosko-Terrasny State Nature Biosphere Reserve (Russia) based on aerial photography by quadrocopter

Nature Conservation Research: Заповедная наука, 2021
In this paper, we investigated three pine (Pinus sylvestris) forest plots (each of 50 × 50 m), different by age and composition, located in the Prioksko-Terrasny State Nature Biosphere Reserve (Moscow Region, Russia). This study was aimed to evaluate the
Natalya V. Ivanova, Maxim P. Shashkov, Vladimir N. Shanin   +2 more
doaj   +1 more source

Prediction of peptide and protein propensity for amyloid formation [PDF]

, 2014
Understanding which peptides and proteins have the potential to undergo amyloid formation and what driving forces are responsible for amyloid-like fiber formation and stabilization remains limited.
A Quintas, A Trovato, A Trovato, AC Davison, AC Tsolis, Alexandre Quintas, AM Fernandez-Escamilla, AP Pawar, AV Finkelstein, B Rost, C Nerelius, Carlos Família, CM Dobson, D Eisenberg, David A. Phoenix, DJ Selkoe, DM Fowler, Eugene A. Permyakov, F Chiti, F Chiti, F Sasagawa, GG Tartaglia, GG Tartaglia, H Hu, I Cherny, I Walsh, IV Baskakov, J Palau, J Tian, JC Rochet, JD Sipe, JM Zimmerman, JW Kelly, JW Kelly, K Rajagopal, KF DuBay, KK Frousios, KT O’Neil, L Goldschmidt, LO Jimenez, M Belli, M Emily, M Hollander, M Kuhn, M López de la Paz, M Oliveberg, M Stefani, M Sunde, M Sunde, M Zamani, MB Kursa, MJ Thompson, MT Pastor, N Becker, N Qian, O Conchillo-Solé, PK Teng, PY Chou, RS Harrison, S Idicula-thomas, S Kawashima, S Kawashima, S Maurer-Stroh, S Ventura, S Yoon, S Yoon, Sarah R. Dennison, SJ Hamodrakas, SJ Hamodrakas, SK Maji, SO Garbuzynskiy, T Hothorn, T Hothorn, T Hothorn, T Scheibel, TPJ Knowles, VS Mathura, WH DePas, WT Astbury, Y Kallberg, Ž Eva   +80 more
core   +5 more sources

Change in aggregate structure of various soil types during the succession of abandoned lands

Бюллетень Почвенного института им. В.В. Докучаева, 2017
A comparative analysis of the changes in the aggregate structure in various types of soils (Sod-podzolic, Gray forest, and Chernozems) during their postagrogenic evolution was carried out.
Yu. I. Baeva, I. N. Kurganova, V. O. Lopes De Gerenyu, L. A. Ovsepyan, V. M. Telesnina, Yu. D. Tsvetkova   +5 more
doaj   +1 more source

A Factor Graph Approach to Automated GO Annotation [PDF]

, 2016
As volume of genomic data grows, computational methods become essential for providing a first glimpse onto gene annotations. Automated Gene Ontology (GO) annotation methods based on hierarchical ensemble classification techniques are particularly ...
Elizabeth Tapia, Fernando Roda, Flavia Krsticevic, Flavio E Spetale, Pilar Bulacio   +4 more
core   +3 more sources

Self-assembly of Tween 80 micelles as nanocargos for oregano and trans-cinnamaldehyde plant-derived compounds [PDF]

, 2020
The self-assembly of Tween 80 (T80) micelles loaded with plant-based oregano essential oil (OR) and trans-cinnamaldehyde (TCA) was studied. The effect of different factors, including the surfactant to oil ratio, the presence of sodium chloride, thermal ...
Claeys, Myriam, Devlieghere, Frank, Sedaghat Doost, Ali, Stevens, Christian, Van der Meeren, Paul   +4 more
core   +1 more source

Cellular-automata model of the dwarf shrubs populations and communities dynamics [PDF]

Сибирский лесной журнал, 2015
The probabilistic cellular-automata model of development and long-time dynamics of dwarf shrub populations and communities is developed. It is based on the concept of discrete description of the plant ontogenesis and joint model approaches in terms of ...
A. S. Komarov, E. V. Zubkova, P. V. Frolov   +2 more
doaj   +1 more source

Evaluation of biomarkers in the studies of keloid tissue after laser therapy

Медицинский совет, 2022
In this paper, we discuss what biomarkers to choose if there is a need to describe the results of laser therapy targeting keloid skin. We elevate the known cytomarkers (Krt14, Lgals7, Krt5, Dcn, Lum, Igfbp5, Cd31, Vwf, Stambpl1, Uqcrb, Cd3 and Acta2 ...
A. V. Mezentsev, M. M. Karapetyan, V. V. Sobolev, O. V. Zhukova, I. M. Korsunskaya   +4 more
doaj   +1 more source

Assessing the freshwater quality of a large-scale mining watershed : the need for integrated approaches [PDF]

, 2019
Water quality assessments provide essential information for protecting aquatic habitats and stakeholders downstream of mining sites. Moreover, mining companies must comply with environmental quality standards and include public participation in water ...
Arroyo, Nilton Deza, Beeckman, Eveline, De Saeyer, Nancy, De Schamphelaere, Karel, Forio, Marie Anne Eurie, Goethals, Peter, Mercado Garcia, Daniel, Sanchez Peña, Marco, Van Buggenhoudt, Cécile, Van Butsel, Jana, Wyseure, Guido   +10 more
core   +1 more source

The Protection of Building Materials of Historical Monuments with Nanoparticle Suspensions

Heritage, 2021
Marble and limestone have been extensively used as building materials in historical monuments. Environmental, physical, chemical and biological factors contribute to stone deterioration.
Efstathia I. Pavlakou, Anastasios G. Agrafiotis, Theokleiti G. Tsolaki, Christine Lemonia, Emily Zouvani, Christakis A. Paraskeva, Petros G. Koutsoukos   +6 more
doaj   +1 more source