Results 51 to 60 of about 5,384,174 (318)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Chandra Spectroscopy Of The Hot Star β Crucis And The Discovery Of A Pre-Main-Sequence Companion [PDF]

, 2008
In order to test the O star wind-shock scenario for X-ray production in less luminous stars with weaker winds, we made a pointed 74-ks observation of the nearby early B giant, beta Crucis (beta Cru; B0.5 III), with the Chandra High Energy Transmission ...
Cohen, David H., Gagné, M., Jensen, Eric L.N., Kuhn, Michael Ascher, , \u2707, Miller, N. A.   +4 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Hadron Identification Prospects with Granular Calorimeters

Particles
In this work we consider the problem of determining the identity of hadrons at high energies based on the topology of their energy depositions in dense matter, along with the time of the interactions.
Andrea De Vita, Abhishek, Max Aehle, Muhammad Awais, Alessandro Breccia, Riccardo Carroccio, Long Chen, Tommaso Dorigo, Nicolas R. Gauger, Ralf Keidel, Jan Kieseler, Enrico Lupi, Federico Nardi, Xuan Tung Nguyen, Fredrik Sandin, Kylian Schmidt, Pietro Vischia, Joseph Willmore   +17 more
doaj   +1 more source

Irreversible Adsorption from Dilute Polymer Solutions

, 2003
We study irreversible polymer adsorption from dilute solutions theoretically. Universal features of the resultant non-equilibrium layers are predicted.
Addad, Addad, Addad, Adriani, Amit, Aubouy, Auvray, Auvray, Auvray, B. O'Shaughnessy, Barford, Barford, Bouchaud, Brown, Chakraborty, Cosgrove, Cosgrove, Cosgrove, Creton, D. Vavylonis, De'Bell, Deruelle, Douglas, Duplantier, Durning, Edwards, Eisenriegler, Feller, Frantz, Frantz, Frantz, Fu, Fu, Gennes, Gennes, Gennes, Gennes, Guiselin, Hlady, Joannis, Johner, Johnson, Jones, Kawaguchi, Konstadinidis, Konstadinidis, Lai, Laible, Lee, Lee, Lenk, Léger, Marzolin, Mubarekyan, Mubarekyan, O'Shaughnessy, O'Shaughnessy, O'Shaughnessy, O'Shaughnessy, O'Shaughnessy, Pefferkorn, Pefferkorn, physics, Pietronero, Ponomarev, Scheutjens, Scheutjens, Schlenoff, Schneider, Schneider, Semenov, Semenov, Semenov, Shaffer, Shaffer, Shaffer, Soga, Soga, Sundararaj, Talbot, Tsao, Varoqui, Zajac   +82 more
core   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Compromise projections for world maps – an optimization approach using discrete global grid systems and principles from classical mechanics

International Journal of Digital Earth
Projections for world maps can only be a compromise between different requirements as it is impossible to construct a projection that preserves distances, areas, and angles.
Franz-Benjamin Mocnik
doaj   +1 more source

Improved Orbital Parameters And Transit Monitoring For HD 156846b [PDF]

, 2013
HD 156846b is a Jovian planet in a highly eccentric orbit (e = 0.85) with a period of 359.55 days. The pericenter passage at a distance of 0.16 AU is nearly aligned to our line of sight, offering an enhanced transit probability of 5.4% and a potentially ...
Ciardi, D. R., Dragomir, D., Fischer, D. A., Henry, G. W., Howard, A. W., Jensen, Eric L.N., Kane, S. R., Laughlin, G., Mahadevan, S., Pilyavsky, G., Ramirez, S. V., Von Braun, K., Wright, J. T.   +12 more
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Supercritical Conversion Of The 3rd Blue Phase To The Isotropic-Phase In A Highly Chiral Liquid-Crystal [PDF]

, 1995
The results of two independent experiments in the vicinity of the “transition” from the third blue phase ( BPIII) to isotropic phase ( I) are reported for a highly chiral liquid crystal.
Collings, Peter J., Garland, C. W., Kutnjak, Z., Passmore, J. Loren   +3 more
core   +2 more sources