Results 71 to 80 of about 6,323,792 (390)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Physics-informed machine learning

Nature Reviews Physics, 2021
G. Karniadakis, I. Kevrekidis, Lu Lu, P. Perdikaris, Sifan Wang, Liu Yang   +5 more
semanticscholar   +1 more source

Constraints On Porosity And Mass Loss In O-Star Winds From The Modeling Of X-Ray Emission Line Profile Shapes [PDF]

, 2013
We fit X-ray emission line profiles in high resolution XMM-Newton and Chandra grating spectra of the early O supergiant zeta Pup with models that include the effects of porosity in the stellar wind.
Cohen, David H., Leutenegger, M. A., Owocki, S. P., Sundqvist, J. O.   +3 more
core   +1 more source

Hadron Identification Prospects with Granular Calorimeters

Particles
In this work we consider the problem of determining the identity of hadrons at high energies based on the topology of their energy depositions in dense matter, along with the time of the interactions.
Andrea De Vita, Abhishek, Max Aehle, Muhammad Awais, Alessandro Breccia, Riccardo Carroccio, Long Chen, Tommaso Dorigo, Nicolas R. Gauger, Ralf Keidel, Jan Kieseler, Enrico Lupi, Federico Nardi, Xuan Tung Nguyen, Fredrik Sandin, Kylian Schmidt, Pietro Vischia, Joseph Willmore   +17 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

KELT-18b: Puffy Planet, Hot Host, Probably Perturbed [PDF]

, 2017
We report the discovery of KELT-18b, a transiting hot Jupiter in a 2.87-day orbit around the bright ( V = 10.1), hot, F4V star BD+60 1538 (TYC 3865-1173-1).
Baldrige, A., Baştürk, Ö., Beatty, T. G., Benni, P., Berlind, P., Bieryla, A., Calkins, M. L., Cohen, David H., Collins, K. A., Colón, K. D., Curtis, I. A., DePoy, D. L., Eastman, J. D., Esquerdo, G. A., Fukui, A., Fulton, B. J., Gaudi, B. S., Gregorio, J., Howard, A. W., Isaacson, H., Jensen, Eric L.N., Joner, M. D., Kempton, E. M.-R., Kielkopf, J. F., Labadie-Bartz, J., Latham, D. W., Lund, M. B., Manner, M., Marshall, J. L., McLeod, K. K., Melton, C., Narita, N., Oberst, T. E., Oelkers, R. J., Penev, K., Penny, M. T., Pepper, J., Pogge, R. W., Reed, P. A., Relles, H., Rodriguez, J. E., Scarpetta, G., Siverd, R. J., Stassun, K. G., Stephens, D. C., Stevens, D. J., Stockdale, C., Tan, T. G., Tirrell, B., Trueblood, M., Trueblood, P., Tsuguru, R., Visgaitis, T., Weiss, L. M., Zambelli, R., Zhao, Y. S., Zhou, G.   +56 more
core   +2 more sources

Numerical Modeling Of Hohlraum Radiation Conditions: Spatial And Spectral Variations Due To Sample Position, Beam Pointing, And Hohlraum Geometry [PDF]

, 2005
View-factor simulations are presented of the spatially varying radiation conditions inside double-ended gold Hohlraums and single-ended gold Hohlraums (\u27\u27 halfraums \u27\u27) used in inertial confinement fusion and high-energy density physics ...
David H. Cohen, Joseph J. MacFarlane, Otto L. Landen, Paisner J. A.   +3 more
core   +3 more sources

Compromise projections for world maps – an optimization approach using discrete global grid systems and principles from classical mechanics

International Journal of Digital Earth
Projections for world maps can only be a compromise between different requirements as it is impossible to construct a projection that preserves distances, areas, and angles.
Franz-Benjamin Mocnik
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Magnetothermodynamics: Measurements Of The Thermodynamic Properties In A Relaxed Magnetohydrodynamic Plasma [PDF]

, 2018
We have explored the thermodynamics of compressed magnetized plasmas in laboratory experiments and we call these studies ‘magnetothermodynamics’. The experiments are carried out in the Swarthmore Spheromak eXperiment device.
Barbano, Luke J., , \u2718, Brown, Michael R., Kaur, M., Light, A. D., Meyer, T., Schaffner, D. A., Shrock, Jaron E., , \u2718, Suen-Lewis, Emma M., , \u2718, Woodruff, S.   +8 more
core   +1 more source