Results 31 to 40 of about 188,895 (243)

Crystal Ball: On the Future High Energy Colliders [PDF]

open access: yes, 2015
High energy particle colliders have been in the forefront of particle physics for more than three decades. At present the near term US, European and international strategies of the particle physics community are centered on full exploitation of the ...
Shiltsev, Vladimir
core  

Search for Cold Dark Matter and Solar Neutrinos with GENIUS and GENIUS-TF

open access: yes, 2002
The new project GENIUS will cover a wide range of the parameter space of predictions of SUSY for neutralinos as cold dark matter. Further it has the potential to be a real-time detector for low-energy (pp and 7Be) solar neutrinos.
H. V. Klapdor-Kleingrothaus   +20 more
core   +2 more sources

Physics Opportunities with the FCC-hh Injectors [PDF]

open access: yes, 2017
In this chapter we explore a few examples of physics opportunities using the existing chain of accelerators at CERN, including potential upgrades. In this context the LHC ring is also considered as a part of the injector system.
Bai, M.   +16 more
core   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Physics at LHC [PDF]

open access: yes, 2006
The prospects for physics at the LHC are discussed, starting with the foretaste, preparation (and perhaps scoop) provided by the Tevatron, in particular, and then continuing through the successive phases of LHC operation. These include the start-up phase,
Ellis, John
core   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Recent results of the CMS experiment

open access: yes, 2014
The CMS experiment is a multi-purpose detector successfully operated at the LHC where predominantly pp collisions take place at various centre-of-mass energies up to sqrt(s)=8 TeV so far.
Sonnenschein, Lars
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Accelerator physics at LEP [PDF]

open access: yesReports on Progress in Physics, 2000
Accelerator physics issues and their influence on performance are presented for the Large Electron-Positron (LEP) storage ring at CERN in Geneva, Switzerland. After several years of operation on the Z boson resonance at beam energies around 45 GeV, the beam energy was increased in steps to over 100 GeV. The major power loss to synchrotron radiation and
D Brandt   +4 more
openaire   +1 more source

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