Results 41 to 50 of about 37,905 (263)

Conceptual design of a nonscaling fixed field alternating gradient accelerator for protons and carbon ions for charged particle therapy [PDF]

, 2013
The conceptual design for a nonscaling fixed field alternating gradient accelerator suitable for charged particle therapy (the use of protons and other light ions to treat some forms of cancer) is ...
Wilson P, J. Strachan, J. H. Cobb, P. A. McIntosh, Edgecock TR, Witte, H., Cobb, JH, Tygier S, Edgecock, T. R., Rochford J, P. Wilson, Easton, MJ, Sheehy, SL, Owen HL, Smith, SL, J. Rochford, Machida, S., Wilson, P., Strachan, J, Prior, C.R., Vojnovic, B, Witte H, R. Fenning, Owen, H.L., Barlow, R. J., Vojnovic, B., J. Pasternak, R. Seviour, Pattalwar, S., S. Tygier, Barlow RJ, Jones, B., Machida, S, Cobb JH, Yokoi, T., Beard, CD, Edgecock, TR, Gardner, I.S.K., N. Bliss, Pattalwar, S, Kelliher, DJ, C. D. Beard, I. S. K. Gardner, Fenning, R., Fenning R, B. Vojnovic, McIntosh, P.A., Strachan J, T. R. Edgecock, A. Khan, Seviour, R., Jones B, Cobb, J. H., Aslaninejad M, Prior, CR, Owen, HL, Hill, M. A., Smith, S. L., Pozimski J, Peach, K.J., Peach, K. J., Seviour R, M. J. Easton, Rochford, J, Cobb, John, Seviour, R, Easton, M. J., Beard, C. D., Gardner, I. S. K., Prior, C. R., B. Jones, Beard, C.D., Seviour, Rebecca, Strachan, J., Gardner ISK, Smith SL, Cobb, J.H., Jones, T., Easton, M.J., Aslaninejad, M, Pasternak, J., S. L. Sheehy, Jones, T, C. R. Prior, Kelliher, D. J., D. J. Kelliher, Wilson, P, Yokoi, T, Yokoi T, McIntosh PA, Rogers CT, Rogers, C.T., M. A. Hill, S. L. Smith, Peach, KJ, Pasternak, J, Vojnovic, Boris, Hill MA, S. Machida, Pozimski, J, Johnstone, CJ, Owen, H. L., R. J. Barlow, Gardner, ISK, C. J. Johnstone, Beard CD, H. L. Owen, H. Witte, Gardner, I. S.K., Jones, B, Hill, M.A., Witte, H, J. Pozimski, Rochford, J., Machida S, Jones T, T. Yokoi, Khan, A., Prior CR, Pattalwar S, Bliss, N., Johnstone CJ, Tygier, S., Peach, Ken, McIntosh, PA, Rogers, C. T., Edgecock, R., Kelliher, D.J., Peach KJ, Pozimski, J., Khan, A, Barlow, R.J., M. Aslaninejad, Johnstone, C.J., Sheehy SL, Vojnovic B, C. T. Rogers, Tygier, S, Johnstone, C. J., McIntosh, P. A., Kelliher DJ, Barlow, RJ, Jones, Bleddyn, S. Pattalwar, Sheehy, S. L., Pasternak J, Aslaninejad, M., Bliss N, Khan A, Easton MJ, T. Jones, Rogers, CT, K. J. Peach, Fenning, R, Gardner, I. S K, Hill, MA, Smith, S.L., Bliss, N   +157 more
core   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

Compensation Techniques in Accelerator Physics [PDF]

, 2011
Accelerator physics is one of the most diverse multidisciplinary fields of physics, wherein the dynamics of particle beams is studied. It takes more than the understanding of basic electromagnetic interactions to be able to predict the beam dynamics, and
Sayed, Hisham Kamal
core   +1 more source

Bayesian Optimization Algorithms for Accelerator Physics

, 2023
Accelerator physics relies on numerical algorithms to solve optimization problems in online accelerator control and tasks such as experimental design and model calibration in simulations.
Lübsen, Jannis O., Simone Maria Liuzzo, Streeter, Matthew J.V.; id_orcid, Zhang, Zhe, Jannis O. Lübsen, Christopher Mayes, Huang, Xiaobiao, Brahim Mustapha, Verena Kain, Edelen, Auralee L, Xu, Chenran, Fuhao Ji, Garcia, Andrea Santamaria, Liuzzo, Simone Maria, Kennedy, Dylan, Willie Neiswanger, Neiswanger, Willie, Lübsen, Jannis, Jan Kaiser, Angel Ferran Pousa, Jose Martinez, Hunag, Xiaobiao, Isenberg, Natalie M., Annika Eichler, Weijian Lin, Nikita Kuklev, Kaiser, Jan, Lin, Weijian, Xiaobiao Huang, Daniel Ratner, Kain, Verena, Mayes, Christopher, Ryan Roussel, Santamaria Garcia, Andrea, Tobias Boltz, Dylan Kennedy, Natalie M. Isenberg, Jason St. John, Edelen, Auralee L., Martinez, Jose, Lübsen, Jannis O, Pousa, Angel Ferran, Mustapha, Brahim, Streeter, Matthew J.V., Streeter, Matthew J.V, St. John, Jason, Auralee L. Edelen, Yuan Gao, Kuklev, Nikita, Zhe Zhang, Ratner, Daniel, Lehe, Remi, Lin, Wejian, Andrea Santamaria Garcia, Streeter, Metthew J. V., Boltz, Tobias, Eichler, Annika, Ferran Pousa, Angel, Roussel, Ryan, Gao, Yuan, Matthew J. V. Streeter, Isenberg, Natalie M, Matrinez, Jose, Ji, Fuhao, Chenran Xu, Remi Lehe   +65 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Nonlinear problems in accelerator physics

, 1993
In the following report we want to review nonlinear problems in accelerator physics. Theoretical tools and methods are introduced and discussed, and it is shown how these concepts can be applied to the study of various nonlinearities in storage rings ...
Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany), Mais, H.   +1 more
core  

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Accelerator Physics Coordinate Conventions [PDF]

, 1993
This document is about the establishment of unique nominal coordinate conventions inside the RHIC accelerator physics RAP(group)
Peggs, S., MacKay, W.
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source