Results 21 to 30 of about 769,788 (151)

On the origin of the gravitational quantization: The Titius--Bode Law

open access: yes, 2005
Action at distance in Newtonian physics is replaced by finite propagation speeds in classical post--Newtonian physics. As a result, the differential equations of motion in Newtonian physics are replaced by functional differential equations, where the ...
Agnese   +29 more
core   +4 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Metan Molekülünün Elektron Etkisiyle İyonlaşma Dinamiğinin Çakışma Tekniği ile İncelenmesi

open access: yesSüleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, 2014
Özet: Karmaşık moleküllerin elektronlarla etkileşimlerinin ayrıntılı bir biçimde anlaşılmasının atom ve molekül fiziği araştırmalarında, kuramsal modellemelerin gelişmesinde önemli bir yeri vardır. Özellikle moleküllerin dinamik yapılarının anlaşılmasına
Nimet IŞIK   +2 more
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Nuclear effects in atomic transitions

open access: yes, 2010
Atomic electrons are sensitive to the properties of the nucleus they are bound to, such as nuclear mass, charge distribution, spin, magnetization distribution, or even excited level scheme.
Adriana Pálffy   +10 more
core   +1 more source

Symmetric ground states for a stationary relativistic mean-field model for nucleons in the nonrelativistic limit [PDF]

open access: yes, 2012
In this paper we consider a model for a nucleon interacting with the $\omega$ and $\sigma$ mesons in the atomic nucleus. The model is relativistic, but we study it in the nuclear physics nonrelativistic limit, which is of a very different nature from the
Esteban, Maria J., Nodari, Simona Rota
core   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Quantum Many-Body Phenomena in Coupled Cavity Arrays

open access: yes, 2008
The increasing level of experimental control over atomic and optical systems gained in the past years have paved the way for the exploration of new physical regimes in quantum optics and atomic physics, characterised by the appearance of quantum many ...
Aichhorn   +96 more
core   +1 more source

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