Results 61 to 70 of about 72,340 (313)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Scalar electroweak multiplet dark matter
Journal of High Energy Physics, 2019 We revisit the theory and phenomenology of scalar electroweak multiplet thermal dark matter. We derive the most general, renormalizable scalar potential, assuming the presence of the Standard Model Higgs doublet, H, and an electroweak multiplet Φ of ...
Wei Chao +3 more
doaj +1 more source
Mirror symmetry for new physics beyond the Standard Model in $4D$ spacetime [PDF]
, 2022 Wanpeng Tan
openalex +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Journal of High Energy Physics, 2017 We introduce a mirror copy of the ordinary fermions and Higgs scalars for embedding the SU(2) L × U(1) Y electroweak gauge symmetry into an SU(2) L × SU(2) R × U(1) B−L left-right gauge symmetry.
Pei-Hong Gu
doaj +1 more source
Journal of High Energy Physics, 2020 The Majoron, the Nambu-Goldstone boson of lepton number symmetry, is an interesting candidate for dark matter as it deeply connects the dark matter and neutrino physics.
Yoshihiko Abe +4 more
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
High-scale leptogenesis with three-loop neutrino mass generation and dark matter
Journal of High Energy Physics, 2017 We demonstrate a common origin for high-scale leptogenesis and three-loop neutrino mass generation. Specifically we extend the standard model by two real singlet scalars, two singly charged scalars carrying different quantum numbers under certain global ...
Pei-Hong Gu
doaj +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Neutrino Frontier Topical Group Report (NF03): Physics Beyond the Standard Model [PDF]
, 2022 Pilar Coloma +3 more
openalex +1 more source