Results 91 to 100 of about 865,236 (332)

Investigation of Lower-limb Tissue Perfusion during Loading [PDF]

open access: yes, 2002
An extant tissue indentor used for amputee residual limb tissue indentation studies was modified to include laser Doppler flowmetry (LDF) to enable measurement of tissue perfusion during indentation.
Silver-Thorn, Barbara
core   +1 more source

Physiologic compliance in engineered small-diameter arterial constructs based on an elastomeric substrate. [PDF]

open access: yes, 2009
Compliance mismatch is a significant challenge to long-term patency in small-diameter bypass grafts because it causes intimal hyperplasia and ultimately graft occlusion.
Abbott   +50 more
core   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Jaw Rotation in Dysarthria Measured With a Single Electromagnetic Articulography Sensor [PDF]

open access: yes, 2017
Purpose This study evaluated a novel method for characterizing jaw rotation using orientation data from a single electromagnetic articulography sensor.
Berry, Jeffrey   +3 more
core   +2 more sources

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Diagnosis of Chronic Constipation

open access: yesThe Korean Journal of Gastroenterology
Patients with chronic constipation (CC) usually complain of mild to severe symptoms, including hard or lumpy stools, straining, a sense of incomplete evacuation after a bowel movement, a feeling of anorectal blockage, the need for digital maneuver to ...
Seon-Young Park
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice

open access: yesMolecular Metabolism, 2017
Objective: Obesity-induced accumulation of ectopic fat in the liver is thought to contribute to the development of insulin resistance, and increased activity of hepatic CB1R has been shown to promote both processes.
Tony Jourdan   +11 more
doaj   +1 more source

Winter Survival of Grasses and Legumes in Subarctic Alaska as Related to Latitudinal Adaptation, Pre-Winter Storage of Food Reserves, and Dry-Matter Concentration in Overwintering Tissues [PDF]

open access: yes, 1993
similar experiments, were to (a) compare winter hardiness in subarctic Alaska of numerous plant species and ecotypes from various latitudinal sources within most species, and (b) seek a better understanding of certain aspects of pre-winter ...
Klebesadel, Leslie J.
core  

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