Results 71 to 80 of about 341,332 (313)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Physiologic variability in the perinatal period. Origins, measurement, and applications.
, 1999 Variability is inherent in all physiologic signals. This variability provides valuable clinical information or may confound physiologic measurements and the interpretation of results.
Dunster, K. R., Dunster, K R
core +1 more source
ACG Clinical Guidelines: Clinical Use of Esophageal Physiologic Testing [PDF]
, 2020 Esophageal symptoms are common and may indicate the presence of gastroesophageal reflux disease (GERD), structural processes, motor dysfunction, behavioral conditions, or functional disorders. Esophageal physiologic tests are often performed when initial
Gyawali, C. Prakash +16 more
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Feasibility of in-home monitoring for people with glaucoma: the I-TRAC mixed-methods study
Health Technology AssessmentBackground Glaucoma is a chronic disease of the optic nerve and a leading cause of severe visual loss in the UK. Once patients have been diagnosed, they need regular monitoring at hospital eye services.
Carrie Stewart +13 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Architecture of the Basic Physiologic Recorder
, 2010 Signals are acquired from medical instrumentation of many different types. They can be as small as a digital thermometer or as big as a magnetic resonance scanner. In spite of the differences in size, cost, and the type of data these devices obtain, most
Jason Ng +3 more
core +1 more source
Use of Physiologic Reasoning to Diagnose and Manage Shock States [PDF]
, 2011 Shock states are defined by stereotypic changes in well-known physiologic parameters. While these well-known changes provide a convenient entry point into further evaluation of patients in shock or at risk for shock, use of such physiologic evaluation is
Geoffrey Lighthall
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Brazilian Journal of Otorhinolaryngology, 2012 Poucos trabalhos desde a década de 70 foram realizados a fim de elucidar a prova calórica em alterações da orelha média, apesar de inúmeras controvérsias que este exame pode trazer em estruturas anatômicas tão distintas.
Lucia Kazuko Nishino, Lidio Granato
doaj +1 more source