Results 31 to 40 of about 668,135 (297)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

The human gut microbiome and aging

open access: yesGut Microbes
The composition of the human gut microbiome has been observed to change over the course of an individual’s life. From birth, it is shaped by mode of delivery, diet, environmental exposures, geographic location, exposures to medications, and by aging ...
Evan Bradley, John Haran
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Estimulação calórica a ar em mastoidectomias abertas unilaterais Air caloric test in canal wall down mastoidectomy

open access: yesBrazilian Journal of Otorhinolaryngology, 2012
Poucos trabalhos desde a década de 70 foram realizados a fim de elucidar a prova calórica em alterações da orelha média, apesar de inúmeras controvérsias que este exame pode trazer em estruturas anatômicas tão distintas.
Lucia Kazuko Nishino, Lidio Granato
doaj   +1 more source

A Manual of Physiology Physiology Elementary Physiology [PDF]

open access: yesNature, 1896
WE have at the present time several very excellent text-books of physiology in English, adapted for the various needs of different classes of students. And to prevent these being inconveniently increased, it is a matter of tacit agreement amongst teachers of physiology that it is undesirable to afford a welcome to any new text-book, unless it has ...
openaire   +1 more source

Physiological breeding

open access: yesCurrent Opinion in Plant Biology, 2016
Physiological breeding crosses parents with different complex but complementary traits to achieve cumulative gene action for yield, while selecting progeny using remote sensing, possibly in combination with genomic selection. Physiological approaches have already demonstrated significant genetic gains in Australia and several developing countries of ...
Reynolds, Matthew, Langridge, Peter
openaire   +2 more sources

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The utilization spectrum of cardiac output monitoring devices among anesthesiology programs across Veterans Health Administration in the United States

open access: yesAnnals of Cardiac Anaesthesia, 2019
Background: Electronic monitoring of physiologic variables has gained widespread support over the past decade for critical patients in the intensive care setting.
Jahan Porhomayon   +3 more
doaj   +1 more source

Effects of a Peripherally Restricted Hybrid Inhibitor of CB1 Receptors and iNOS on Alcohol Drinking Behavior and Alcohol-Induced Endotoxemia

open access: yesMolecules, 2021
Alcohol consumption is associated with gut dysbiosis, increased intestinal permeability, endotoxemia, and a cascade that leads to persistent systemic inflammation, alcoholic liver disease, and other ailments.
Luis Santos-Molina   +10 more
doaj   +1 more source

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