Results 51 to 60 of about 133,198 (274)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Physiological responses of race car drivers in authentic and simulated motor-racing

open access: yesFrontiers in Sports and Active Living
ObjectivesThe aim of the present investigation was to determine the influence of G-loading and psycho-emotional stress and competitive pressures on driver physiology between authentic and simulated racing during similar environmental conditions (e.g., a hot cockpit).MethodsAuthentic racing data was collected during the 2018 “Sahlen's 6 h at the Glen ...
Justin Holland   +2 more
openaire   +3 more sources

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

INHERITANCE OF PATHOGENICITY AND UREDIOSPORE COLOR IN CROSSES BETWEEN PHYSIOLOGIC RACES OF OAT STEM RUST

open access: yes, 1949
In the F1 generation of crosses between physiologic races 7 (orange) and 11 (red) of Puccinia graminis Pers. var. Avenae Erikss. and Henn., the medium sized uredia (type 2 infection) formed by race 11 on the oat variety White Tartar were dominant to the
T. Johnson
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Optimal Rules for Patent Races [PDF]

open access: yes
There are two important rules in a patent race: what an innovator must accomplish to receive the patent and the allocation of the benefits that flow from the innovation.
Karl Schmedders   +2 more
core  

COMPORTAMENTO FISIOLÓGICO DE DIFERENTES GRUPOS GENÉTICOS DE OVINOS CRIADOS NO SEMIÁRIDO PARAIBANO

open access: yesRevista Caatinga, 2011
The present study had as objective evaluates the physiologic behavior of different genetic groups of sheep created in the semi-arid paraibano in the dry and rainy times.
WANDA MARIA DE ALENCAR XAVIER BEZERRA   +4 more
doaj  

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Physiologic races of Fusarium oxysporum f.Sp. Melonis in the Southeastern Anatolia Region of Turkey and varietal reactions to races of the pathogen

open access: yes, 2002
Thirty-four isolates of Fusarium oxysporum f.sp. melonis (F.o.m.) obtained from 205 fields in melon-producing areas in the southeastern Anatolia Region of Turkey were identified on the basis of colony morphology and pathogenicity by the root dip method ...
Yetisir H., Baran B., Kurt S., Sari N.
core   +1 more source

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