Results 131 to 140 of about 4,767,765 (294)

Comparative study of the effect of water stress on morphological, physiological and biochemical parameters of three Aloe species

Cogent Food & Agriculture
Water stress is one of the most significant abiotic constraints affecting plant growth and limiting agricultural productivity. This study aims to optimize agricultural production and promote the medicinal and cosmetic uses of Aloe plants in Morocco’s ...
Mourad Derouiche, Fadoua Chkird, Anass Alla, Hajar Hamdaoui, Sabir Ouahhoud, Redouane Benabess, Ibtissam Mzabri, Abdelbasset Berrichi, Youssouf Ali Younous, Pravin Badhe, Khalid S. Almaary, Noureddine Kouddane   +11 more
doaj   +1 more source

Physiology [PDF]

Science, 1898
openaire   +4 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Editorial: Human Molecular and Physiological Responses to Hypoxia

Frontiers in Physiology, 2022
Sandro Malacrida, Giacomo Strapazzon, Simona Mrakic-Sposta, Matiram Pun, Annalisa Cogo, Annalisa Cogo, Annalisa Cogo   +6 more
doaj   +1 more source

Physiological Response and Endurance of Madurese Cattle and Their Crosses at The Tropical Environment in Pamekasan Regency

Jurnal Agripet
This study aimed to determine the physiological response of Madura cattle and Limura cattle (Limousin x Madura) to the tropical environment. The research was conducted in Galis District, Pamekasan Regency from July to August 2024. The sample consisted of
Desi Kurniati Agustina, Nurul Hidayati
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Assessing virtual reality presence through physiological measures: a comprehensive review

Frontiers in Virtual Reality
This review analyzes 94 articles in an attempt to define the concept of presence in virtual reality (VR). Two types of data were examined: physiological variables and questionnaires, which were used in 85% study of the selected articles.
Danping Wang, Danping Wang, Yunchao Peng, Yunchao Peng, Lise Haddouk, Lise Haddouk, Nicolas Vayatis, Nicolas Vayatis, Pierre-Paul Vidal, Pierre-Paul Vidal, Pierre-Paul Vidal, Pierre-Paul Vidal   +11 more
doaj   +1 more source

Improved methods for counting bacteria in physiological fluids [PDF]

, 1974
Bacterial population detection is based on detection of adenosine triphosphate (ATP), chemical present in all living matter. Amount of ATP in sample, after chemically removing all nonbacterial ATP, is directly related to bacterial population. Sensitivity
Picciolo, G. L.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source