Results 51 to 60 of about 116,414 (298)

An open affective platform

open access: yes, 2012
Affective computer interfaces improve human-computer interaction by enabling the communication of the user's emotional state. To this end, subtle non-verbal methods of communication provide a rich source of information which may provide valuable ...
Terry Koziniec   +6 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Detecting Music-Induced Emotion Based on Acoustic Analysis and Physiological Sensing: A Multimodal Approach

open access: yes, 2022
The subjectivity of listeners’ emotional responses to music is at the crux of optimizing emotion-aware music recommendation. To address this challenge, we constructed a new multimodal dataset (“HKU956”) with aligned peripheral ...
Xiao Hu, Fanjie Li, Ruilun Liu
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Review of Super-Resolution Single-Molecule Localization Microscopy Cluster Analysis and Quantification Methods

open access: yesPatterns, 2020
Single-molecule localization microscopy (SMLM) is a relatively new imaging modality, winning the 2014 Nobel Prize in Chemistry, and considered as one of the key super-resolution techniques.
Ismail M. Khater   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

HRV and Stress: A Mixed-Methods Approach for Comparison of Wearable Heart Rate Sensors for Biofeedback

open access: yesIEEE Access, 2021
Stress is one of the most significant health problems in today's world. Existing work has used heart rate variability (HRV) to detect stress and provide biofeedback in order to regulate it.
Muhammad Umair   +3 more
doaj   +1 more source

Physiological Computing Education: Towards Teaching Using Physiological Signals

open access: yes, 2022
Electronic Thesis or DissertationPhysiological computing is a novel technology revolutionizing fields outside medical disciplines. Recently, there are multiple implementations of physiological data in educational contexts (e.g., user state monitoring and
Hernandez-Cuevas, Bryan Yomar
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Home - About - Disclaimer - Privacy