Results 61 to 70 of about 116,414 (298)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A novel and innovative cancer classification framework through a consecutive utilization of hybrid feature selection

open access: yesBMC Bioinformatics, 2023
Cancer prediction in the early stage is a topic of major interest in medicine since it allows accurate and efficient actions for successful medical treatments of cancer.
Rajul Mahto   +7 more
doaj   +1 more source

Multimodal Assessment of Interest Levels in Reading: Integrating Eye-Tracking and Physiological Sensing

open access: yesIEEE Access, 2023
Interest in the context of reading holds special significance as it serves as a driving force for learning and education. By understanding and leveraging students’ interests, educators can create more effective and enjoyable learning environments ...
Jayasankar Santhosh   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

ROBIN: activity based robot management system [PDF]

open access: yes, 2010
This paper examines the design and implementation of a system to support firefighting exercises based on tools and ideas of pervasive computing. Through this development a range of technologies and conceptual tools were used, such as sensors, wireless ...
Hadorn, Benjamin   +9 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Near‐Sensor Reservoir Computing for Gait Recognition via a Multi‐Gate Electrolyte‐Gated Transistor

open access: yesAdvanced Science, 2023
The recent emergence of various smart wearable electronics has furnished the rapid development of human–computer interaction, medical health monitoring technologies, etc.
Xuerong Liu   +9 more
doaj   +1 more source

Behavioral and Physiological Responses to Computers in the Ultimatum Game [PDF]

open access: yesInternational Journal of Technology and Human Interaction, 2019
This article describes how studies in the area of decision-making suggest clear differences in behavioral responses to humans versus computers. The current objective was to investigate decision-making in an economic game played only with computer partners. In Experiment 1, participants were engaged in the ultimatum game with computer agents and regular
Aleksandra Swiderska   +2 more
openaire   +3 more sources

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