Results 251 to 260 of about 475,290 (309)

From Stress to Substance Use Disorders: The Expanding Role of Microglia-Astrocyte Crosstalk in Neuroimmune and Glutamate Alterations in the Nucleus Accumbens. [PDF]

Int J Mol Sci
Cancela LM, Mongi-Bragato B, Avalos MP, Bollati FA.   +3 more
europepmc   +1 more source

Role of cuproptosis in digestive system tumors (Review). [PDF]

Int J Mol Med
Zhang L, Cheng Y, Tang L, Zhu J, Tuo B.
europepmc   +1 more source

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Physiological Modeling of Concentration-Effect Relationship for Nondepolarizing Neuromuscular Blocking Drugs

2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2020
This paper reports modeling of physiological processes of neuromuscular transmission considering effects of nondepolarizing neuromuscualr blocking drugs (NDNBs) used during general anesthesia. NDNBs are considered to act by interacting with acetylcohine receptors located at pre- and post-junctional sites.
Hikaru, Hoshino, Eiko, Furutani, Tomonori, Sugawara, Toshihiro, Takeda, Yoshiharu, Sawanobori, Gotaro, Shirakami   +5 more
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Effect of some physiologically important drugs on the skin impedance

Medical & Biological Engineering & Computing, 1981
The impedance of rabbit skin has been measured in the frequency range 1–60 kHz using a simple a.c. bridge method and stainless steel electrodes. The effect of four important drugs, namely, adrenaline, noradrenaline, atropine and histamine, has been examined. It was found that all these drugs produced a decrease in the skin impedance in varying degrees,
J, Behari, D V, Rai
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Acute behavioral and physiological effects of modafinil in drug abusers

Behavioural Pharmacology, 2002
Modafinil, a novel stimulant, is effective in the treatment of excessive daytime sleepiness associated with narcolepsy. It is biochemically and pharmacologically distinct from prototypical stimulants such as D-amphetamine, cocaine, and methylphenidate. The present experiment was designed to assess the acute behavioral effects of oral modafinil, cocaine,
C R, Rush, T H, Kelly, L R, Hays, R W, Baker, A F, Wooten   +4 more
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Physiological and Laboratory Markers of Drug Effect

2007
This chapter focuses on physiological and laboratory markers of drug effect. The selection and measurement of relevant drug effects are important parts of clinical pharmacology. The biomarkers have served as surrogate endpoints and have provided the basis for regulatory approval of new drugs.
ARTHUR J. ATKINSON, PAUL ROLAN
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Adverse Effects of Drugs on Bone and Calcium Metabolism/Physiology

Clinical Reviews in Bone and Mineral Metabolism, 2007
Drugs may affect bone turnover and density in many ways. However, the disease for which the drugs are administered may also contribute to bone loss. Infection with human immunodeficiency virus leads to a loss of bone mineral, while treatment with highly active antiretroviral therapy does not seem to contribute to further bone loss.
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Basic concepts of ion channel physiology and anaesthetic drug effects

European Journal of Anaesthesiology, 2003
Ion channels regulate a diversity of physiological functions such as neuronal signalling, cardiac excitability and immune cell response. All of these systems may be affected during the conduct of general as well as local anaesthesia. Thus, the investigation of anaesthetic action on ion channels has become the focus of an increasing number of laboratory
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