Results 71 to 80 of about 175,272,373 (206)

Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast [PDF]

, 2008
To better understand off-target effects of widely prescribed psychoactive drugs, we performed a comprehensive series of chemogenomic screens using the budding yeast Saccharomyces cerevisiae as a model system.
Nislow, Corey, Jan Wildenhain, Giaever, Guri, Guri Giaever, Gebbia, Marinella, Heisler Lawrence E., Tyers Mike, Ericson, Elke, Nislow Corey, Wildenhain, Jan, Corey Nislow, Elke Ericson, Wildenhain Jan, Lawrence E Heisler, Ericson Elke, Gebbia Marinella, Mike Tyers, Marinella Gebbia, Heisler, Lawrence E., Tyers, Mike, Giaever Guri   +20 more
core   +2 more sources

Non-canonical Targets Mediating the Action of Drugs of Abuse: Cocaine at the Sigma-1 Receptor as an Example

Frontiers in Neuroscience, 2019
In addition to acting on traditionally recognized receptors or transporters on the plasma membrane, several drugs of abuse, including amphetamine, methamphetamine, nicotine, opioid, cocaine, ketamine, and cannabinoid, have been shown to exert their ...
Tsung-Ping Su
doaj   +1 more source

Reports of side effects associated with the use of drugs 1968-1975

, 1976
The National Drugs Advisory Board received 716 reports from medical and dental practitioners during 1975. From these 1180 side-effects were recorded associated with the use of drugs during the year.
National Drugs Advisory Board (NDAB)
core  

Acting on hormone receptors with minimal side effect on cell proliferation: a timely challenge illustrated with GLP-1R and GPER.

Frontiers in Endocrinology, 2013
G protein coupled receptors (GPCRs) constitute a large family of receptors that sense molecules outside the cell and activate inside signal transduction pathways and cellular responses.
Véronique eGigoux, Daniel eFourmy
doaj   +1 more source

Reports of side effects associated with the use of drugs 1984

, 1984
During 1984 the National Drugs Advisory Board received 803 reports, from which 1668 side-effects were recorded. Of these, the largest percentages were as follows: Drugs Affecting the Central Nervous System 50% (including Non-Steroidal Anti-lnfammatory
National Drugs Advisory Board (NDAB)
core  

Stimulant drugs and their physiological effects [PDF]

, 2011
The category of stimulant drugs is a heterogenous group of substances which benefit-to-harm ratio varies widely. This work attempts to use a systemic approach in order to characterize the underlying basis of the physiological effects of their selected ...
Nováková, Pavlína
core  

The cerebrovascular effects of adrenaline, noradrenaline and dopamine infusions under propofol and isoflurane anaesthesia in sheep [PDF]

, 2002
Publisher's copy made available with the permission of the publisher © Australian Society of AnaesthetistsInfusions of catecholamines are frequently administered to patients receiving propofol or isoflurane anaesthesia.
Grant, C., Upton, R., Martinez, A., Myburgh, J.   +3 more
core   +1 more source

Reports of side effects associated with the use of drugs, 1992

, 1992
Any drug which is therapeutically active may be associated with side effects (i.e. adverse drug reactions). These in many circumstances are tolerable because of the ultimate beneficial action of the drug.
National Drugs Advisory Board (NDAB)
core  

In-vitro study of the effect of anti-hypertensive drugs on placental hormones and angiogenic proteins synthesis in pre-eclampsia [PDF]

, 2014
Antihypertensive drugs lower the maternal blood pressure in pre-eclampsia (PE) by direct or central vasodilatory mechanisms but little is known about the direct effects of these drugs on placental ...
Muttukrishna, S, Jauniaux, E, Gangooly, Subrata, Jauniaux, Eric, Gangooly, S, Shanthi Muttukrishna, Eric Jauniaux, Muttukrishna, Shanthi, Subrata Gangooly, Gangooly Subrata, Muttukrishna Shanthi, Jauniaux Eric   +11 more
core   +2 more sources

Some physiological effects of psychotropic drugs. [PDF]

British Journal of Clinical Pharmacology, 1976
I, Oswald, V, Bĕxinová
openaire   +2 more sources