Results 71 to 80 of about 326,833 (299)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Effects of electroencephalography-based art therapy on emotion regulation difficulties, psychological well-being, relaxation and attention levels among college students

Humanities & Social Sciences Communications
College students face increasing psychological health challenges, yet effective emotion regulation interventions remain understudied. This study examines whether electroencephalography (EEG) feedback can enhance the effectiveness of art therapy for ...
Ling Wu, Shuxin Wang, Libo Yang, Xin Wu
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Analyzing VR-based group discussions for timely speaking-intention feedback to leaders

Frontiers in Computer Science
IntroductionDespite advances in virtual reality (VR) devices, leaders in VR-based group discussions lack inclusive facilitation support. Speaking-intention cues are latent information indicating readiness to speak, yet they are difficult to perceive in ...
Chenghao Gu, Jiadong Chen, Tianyuan Yang, Feike Xu, Boxuan Ma, Shin'ichi Konomi   +5 more
doaj   +1 more source

The assessment of physiology education by student feedback

, 2015
Recording of pattern visual evoked potentials (pVEP) is a method that allows assessment of visual pathways as a whole. In our study, we aimed to assess pVEP latency and amplitude to checkerboard pattern stimuli presented bilaterally and unilaterally (left and right).
Erdoğan, Hasan, Şener, Ümit, Balkas, Serdar Resul, Soydan, Zekeriya, Sagbas, Miray   +4 more
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Using Open-Loop Experiments to Study Physiological Systems, With Examples From the Human Eye-Movement Systems

, 1989
To analyze the contribution of each element in a sensory feedback control system, it is necessary to study the system with the feedback loop opened. Some physiological systems have multiple or even unknown sources of feedback, which makes it exceedingly
TM Hamm, AT Bahill
core   +1 more source

Am I Top of the Pops? Does Feedback of Live GPS Between Sets of Hurling-Specific Small-Sided Games Improve Subsequent Running and Physiological Performance?

Applied Sciences
The investigation aimed to determine if live feedback of team- and player-specific global positioning system (GPS) running performance data between bouts of hurling small-sided games (SSGs) altered the physical and physiological responses during ...
Shane Malone, John Keane, Tom Hargroves, Conor P. Clancy, John David Duggan, Damien Young, Kieran D. Collins   +6 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Effect of disparities of feedback on pacing in cycle time trials

, 2012
The purpose of this study is to understand the effect of hypoxia during warm-up and competition on performance during cycle time trials. Methods: Seven well-trained subjects performed a VO2max test, two habituation trials, and four randomly ordered ...
Nyberg, Katelyn E.
core