Results 71 to 80 of about 2,517,379 (288)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Frontiers in Virtual RealityBackgroundAugmented sensory feedback (ASF) in virtual reality (VR) can enhance motor performance, yet it is not standardly employed with rehabilitation protocols and its effects on physiological and perceptual states remain underexplored.AimThis study ...
Raviraj Nataraj +9 more
doaj +1 more source
Physiological Control Law for Rotary Blood Pumps with Full-State Feedback Method
Applied Sciences, 2019 One concern about pulsatile rotary blood pumps is their physiological controller reactions when “venous return” changes. When a patient rises from a supine to a standing position, the blood volume in the leg veins is raised, owing to ...
Mohsen Bakouri
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Effect of disparities of feedback on pacing in cycle time trials [PDF]
, 2012 The purpose of this study is to understand the effect of hypoxia during warm-up and competition on performance during cycle time trials. Methods: Seven well-trained subjects performed a VO2max test, two habituation trials, and four randomly ordered ...
Nyberg, Katelyn E.
core
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
VibroTac: An Ergonomic And Versatile Usable Vibrotactile Feedback Device [PDF]
, 2010 — This paper presents an ergonomic vibrotactile feedback device for the human arm. Due to the developed con- cept, the device can be used for a large spectrum of applications and a wide range of arm diameters since vibration segments are self ...
Ende, Tobias +3 more
core
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Humanities & Social Sciences CommunicationsCollege students face increasing psychological health challenges, yet effective emotion regulation interventions remain understudied. This study examines whether electroencephalography (EEG) feedback can enhance the effectiveness of art therapy for ...
Ling Wu, Shuxin Wang, Libo Yang, Xin Wu
doaj +1 more source
Potential Roles of Exercise in Regulating Myoendothelial Feedback in Resistance Arteries [PDF]
운동과학PURPOSE Resistance arteries rely on tightly coordinated signaling between vascular smooth muscle cells (SMCs) and endothelial cells (ECs) to regulate vascular tone and ensure appropriate tissue perfusion.
Young-Min Park, Kwang-Seok Hong
doaj +1 more source