Results 61 to 70 of about 326,833 (299)

Enhancing long-term adherence in elderly stroke rehabilitation through a digital health approach based on multimodal feedback and personalized intervention

open access: yesScientific Reports
Multimodal digital health technologies aim to improve long-term adherence in stroke patients through personalized feedback and psychological monitoring.
Xintong Wen   +7 more
doaj   +1 more source

Physiological Control Law for Rotary Blood Pumps with Full-State Feedback Method

open access: yesApplied Sciences, 2019
One concern about pulsatile rotary blood pumps is their physiological controller reactions when “venous return” changes. When a patient rises from a supine to a standing position, the blood volume in the leg veins is raised, owing to ...
Mohsen Bakouri
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Aprendendo com feedback: um estudo sobre como o cérebro utiliza informação para aprender [PDF]

open access: yes, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em Psicologia.Para aprender, é necessário extrair e integrar informações de diferentes fontes.
Luft, Caroline Di Bernardi
core  

Training-induced modulation of motor task performance and psychophysiological domains through augmented sensory feedback in virtual reality

open access: yesFrontiers in Virtual Reality
BackgroundAugmented sensory feedback (ASF) in virtual reality (VR) can enhance motor performance, yet it is not standardly employed with rehabilitation protocols and its effects on physiological and perceptual states remain underexplored.AimThis study ...
Raviraj Nataraj   +9 more
doaj   +1 more source

Proposal for a Framework for Optimizing Artificial Environments Based on Physiological Feedback [PDF]

open access: yesJournal of PHYSIOLOGICAL ANTHROPOLOGY and Applied Human Science, 2005
We propose and then evaluate a new framework for finding the physical parameters of an artificial environment which give rise to given target physiological characteristics. We assume that a human is a system that takes as inputs the physical parameters of an artificial environment and outputs physiological parameters in response.
Takagi, Hideyuki   +2 more
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Noise management by molecular networks.

open access: yesPLoS Computational Biology, 2009
Fluctuations in the copy number of key regulatory macromolecules ("noise") may cause physiological heterogeneity in populations of (isogenic) cells. The kinetics of processes and their wiring in molecular networks can modulate this molecular noise.
Frank J Bruggeman   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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