Results 91 to 100 of about 818,500 (292)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Automated system for integration and display of physiological response data [PDF]
The system analysis approach was applied in a study of physiological systems in both 1-g and weightlessness, for short and long term experiments. A whole body, algorithm developed as the first step in the construction of a total body simulation system is
core +1 more source
Impact of Sensory Adapted Dental Environment on Children with Developmental Disabilities [PDF]
, 2018 Purpose: This was a pilot study assessing the impact of a sensory adapted dental environment (SADE) on children with developmental disabilities (DD) receiving routine dental care.
Kim, Gail
core +1 more source
Brain–computer interface game applications for combined neurofeedback and biofeedback treatment for children on the autism spectrum [PDF]
, 2014 Individuals with Autism Spectrum Disorder (ASD) show deficits in social and communicative skills, including imitation, empathy, and shared attention, as well as restricted interests and repetitive patterns of behaviors.
Friedrich, Elisabeth V. C. +5 more
core +4 more sources
Integrative Physiology of Coronary Microcirculation.
The Japanese Journal of Physiology, 1999 Coronary microvessels play a crucial role for mechanoenergetic interaction between blood flow and myocardial function, which is not uniform transmurally. Thus, highly organized vascular regulations are required for matching local blood flow with myocardial energy requirement.
F, Kajiya, M, Goto
openaire +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A Microbial Perspective on the Grand Challenges in Comparative Animal Physiology
mSystems, 2018 Interactions with microbial communities can have profound influences on animal physiology, thereby impacting animal performance and fitness. Therefore, it is important to understand the diversity and nature of host-microbe interactions in various animal ...
Kevin D. Kohl
doaj +1 more source
An integrative approach to space-flight physiology using systems analysis and mathematical simulation [PDF]
An approach was developed to aid in the integration of many of the biomedical findings of space flight, using systems analysis. The mathematical tools used in accomplishing this task include an automated data base, a biostatistical and data analysis ...
Leonard, J. I. +2 more
core +1 more source
Integrating sensor streams in pHealth networks [PDF]
, 2008 Personal Health (pHealth) sensor networks are generally used to monitor the wellbeing of both athletes and the general public to inform health specialists of future and often serious ailments.
McCann, Dónall +2 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source